PDF(Pubmed)
Abstract：
Richter\'s syndrome (RS) defines the transformation of chronic lymphocytic leukemia into high-grade lymphoma, which usually involves lymph nodes and bone marrow. Extranodal involvement of the heart is an extremely rare condition. Patients with heart involvement tended to have a low response to chemotherapy and relative poor prognosis. The transformation process of RS is often insidious and nonspecific making it challenging to diagnose.
A 64-year-old woman wih a history of chronic lymphocytic leukemia (CLL) presented with intermittent chest pain and was diagnosed with non-ST-elevation myocardial infarction (NSTEMI). However, the contrast enhanced echocardiography revealed a large irregular mass, measuring about 75.4 mm × 37.5 mm, located on the lateral and posterior wall of the right ventricle. Biopsy of the cardiac mass and the results revealed diffuse large B-cell lymphoma.
We present a case of a 64-year-old woman with aggressive diffuse large B-cell lymphoma involving the heart. This case could provide some insights in the diagnosis of cardiac lymphoma.
A 64-year-old woman wih a history of chronic lymphocytic leukemia (CLL) presented with intermittent chest pain and was diagnosed with non-ST-elevation myocardial infarction (NSTEMI). However, the contrast enhanced echocardiography revealed a large irregular mass, measuring about 75.4 mm × 37.5 mm, located on the lateral and posterior wall of the right ventricle. Biopsy of the cardiac mass and the results revealed diffuse large B-cell lymphoma.
We present a case of a 64-year-old woman with aggressive diffuse large B-cell lymphoma involving the heart. This case could provide some insights in the diagnosis of cardiac lymphoma.
摘要：
背景：Richter综合征（RS）定义了慢性淋巴细胞白血病转化为高级别淋巴瘤，通常涉及淋巴结和骨髓。心脏的结外受累是一种极为罕见的疾病。心脏受累患者对化疗的反应较低，预后相对较差。RS的转化过程通常是阴险且非特异性的，这使得诊断具有挑战性。
方法：一名64岁女性，有慢性淋巴细胞白血病（CLL）病史，表现为间歇性胸痛，被诊断为非ST段抬高型心肌梗死（NSTEMI）。然而,对比增强超声心动图显示一个大的不规则肿块，尺寸约为75.4mm×37.5mm，位于右心室的侧壁和后壁。心脏肿块活检，结果显示弥漫性大B细胞淋巴瘤。
结论：我们介绍了一例64岁女性，患有累及心脏的侵袭性弥漫性大B细胞淋巴瘤。该病例可为心脏淋巴瘤的诊断提供一些见解。
方法：一名64岁女性，有慢性淋巴细胞白血病（CLL）病史，表现为间歇性胸痛，被诊断为非ST段抬高型心肌梗死（NSTEMI）。然而,对比增强超声心动图显示一个大的不规则肿块，尺寸约为75.4mm×37.5mm，位于右心室的侧壁和后壁。心脏肿块活检，结果显示弥漫性大B细胞淋巴瘤。
结论：我们介绍了一例64岁女性，患有累及心脏的侵袭性弥漫性大B细胞淋巴瘤。该病例可为心脏淋巴瘤的诊断提供一些见解。
