关键词: Pterygium surgery autograft impression cytology inferior bulbar conjunctiva superior bulbar conjunctiva

Mesh : Humans Pterygium / surgery Autografts Transplantation, Autologous Cytology Conjunctiva Mucins

来  源:   DOI:10.4274/tjo.galenos.2023.64494   PDF(Pubmed)

Abstract:
UNASSIGNED: This study aimed to evaluate the effect of using an inferior or superior conjunctival autograft in primary pterygium surgery on the postoperative ocular surface.
UNASSIGNED: Forty eyes of 40 patients who underwent pterygium surgery with autograft were included in the study. Cytological cell counts were performed on samples taken from the bulbar conjunctiva by impression cytology before and 1 year after the operation. Schirmer 1 test score, lissamine green conjunctival staining score, tear film break-up time (TBUT), and fluorescein corneal staining scores were evaluated. The pain levels of the patients were evaluated with visual analog scale at postoperative 1 day and 1 week.
UNASSIGNED: Corneal and conjunctival staining, TBUT, and Schirmer test results demonstrated significant improvement in all patient groups after surgery, but there was no difference between groups (p>0.05). In both preoperative and postoperative impression cytology, the number of goblet cells in the inferior bulbar conjunctiva was higher than in the superior bulbar conjunctiva (p<0.001), while there was no such difference in epithelial cell or mucin staining. There were no significant cytological changes postoperatively in either group (p>0.05).
UNASSIGNED: Pterygium surgery with autografting improved tear function tests regardless of graft location. Goblet cell count was higher in the inferior bulbar conjunctiva than in the superior bulbar conjunctiva in both postoperative and preoperative impression cytology. However, there was no significant difference in postoperative epithelial and goblet cell counts or mucin staining between the groups before and after surgery. We think that using the inferior bulbar conjunctiva is an appropriate choice in cases where the superior conjunctiva cannot be used as a graft or when future glaucoma surgery is possible.
摘要:
本研究旨在评估在原发性翼状胬肉手术中使用下结膜或上结膜自体移植物对术后眼表的影响。
40例自体翼状胬肉手术患者的40只眼纳入研究。在手术前和手术后1年,通过印模细胞学检查从球结膜采集的样品进行细胞学细胞计数。Schirmer1考试成绩,lissamine绿色结膜染色评分,泪膜破裂时间(TBUT),评估荧光素角膜染色评分。术后1天和1周用视觉模拟量表评估患者的疼痛程度。
角膜和结膜染色,TBUT,和Schirmer测试结果显示,手术后所有患者组均有显着改善,但组间差异无统计学意义(p>0.05)。在术前和术后印模细胞学中,下球结膜杯状细胞数量高于上球结膜(p<0.001),而上皮细胞或粘蛋白染色没有这种差异。两组患者术后均无明显细胞学改变(p>0.05)。
翼状胬肉自体移植手术改善了泪液功能测试,无论移植位置如何。在术后和术前印模细胞学中,下球结膜的杯状细胞计数均高于上球结膜。然而,术后上皮和杯状细胞计数或粘蛋白染色在手术前后组间无显著差异。我们认为,在不能将上结膜用作移植物或可能进行未来青光眼手术的情况下,使用下球结膜是合适的选择。
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