Abstract:
A woman 12 weeks and 3 days pregnant was referred to the emergency department with significant hypertension which, despite aggressive medical management, remained uncontrolled. Markedly elevated levels of renin and aldosterone beyond what is typical in early pregnancy were present, which together with the finding of a right ovarian cyst pointed to the possible diagnosis of an extrarenal reninoma.and the decision was made to perform a right-sided oophorectomy at 16 weeks gestation. Histology demonstrated a staining pattern most consistent with a steroid cell tumour leading to the diagnosis of refractory hypertension secondary to an ovarian steroid cell tumour. Post oophorectomy blood biochemistry rapidly returned to normal, and our patient\'s hypertension slowly resolved allowing for a large reduction in antihypertensive agent requirements and a successful pregnancy outcome.
摘要:
一名怀孕12周零3天的妇女因患有严重的高血压而被转诊至急诊科,尽管积极的医疗管理,仍然不受控制。肾素和醛固酮水平明显升高,超过了妊娠早期的典型水平,与右卵巢囊肿的发现一起指出了肾外肾癌的可能诊断。并决定在妊娠16周时进行右侧卵巢切除术.组织学显示出与类固醇细胞肿瘤最一致的染色模式,导致诊断为继发于卵巢类固醇细胞肿瘤的难治性高血压。卵巢切除术后血液生化迅速恢复正常,和我们的病人的高血压缓慢解决,允许大幅减少降压药物的需求和成功的妊娠结局。