Abstract:
A man in his early 20s presented to us in the outpatient department with a history of diarrhoea for 4 months. Investigations revealed elevated serum chromogranin levels and an intensely avid lesion in the gastrohepatic ligament in Gallium DOTATATE positron emission tomography (PET). The tumour was excised laparoscopically, and no other lesions were seen. The patient improved clinically and had a normal serum chromogranin level postoperatively. He is currently much improved at the 1year follow-up. We did an extensive workup to look for a primary tumour. It was concluded that it was a de novo tumour arising from the lesser sac. The recommended investigations in case of neuroendocrine tumour (NET) with unknown primary include blood investigations to look for the functional status of the tumour, histopathological examination, including immunohistochemistry, and radiological imaging, which must include a Gallium DOTATATE PET. An isolated NET of the lesser sac has not been reported in the literature.
摘要:
一名20岁出头的男子在门诊部给我们介绍,他有4个月的腹泻史。研究显示,在镓DOTATATE正电子发射断层扫描(PET)中,血清嗜铬粒蛋白水平升高,并且胃肝韧带强烈受损。肿瘤是用腹腔镜切除的,没有看到其他病变。患者在临床上有所改善,术后血清嗜铬粒蛋白水平正常。他目前在1年的随访中得到了很大的改善。我们进行了广泛的检查以寻找原发性肿瘤。结论是这是由小囊引起的从头肿瘤。对于原发性未知的神经内分泌肿瘤(NET),推荐的检查包括血液检查以寻找肿瘤的功能状态,组织病理学检查,包括免疫组织化学,和放射成像,其中必须包括镓掺杂PET。在文献中还没有报道小囊的分离的NET。