PDF(Pubmed)
Abstract：
Faced with the lack of physical activity caused by mandatory home isolation during special periods and patients\' inconvenience in carrying out professionally supervised exercise, many home-based exercise programs have been developed. This systematic review and meta-analysis aimed to examine the effects of home-based exercise on measures of motor symptoms, quality of life and functional performance in Parkinson\'s disease (PD) patients.
We performed a systematic review and meta-analysis, and searched PubMed, MEDLINE, Embase, Cochrane library, and Web of Science from their inception date to April 1, 2023. The quality of the literature was assessed using PEDro\'s quality scale. The data was pooled using R software. Results are presented as pooled standardized mean difference (SMD) with 95% confidence interval (CI).
A total of 20 studies involving 1885 PD patients were included. Meta-analysis results showed that home-based exercise had a small effect in relieving overall motor symptoms in PD patients (SMD = -0.29 [-0.45, -0.13]; P < 0.0001), improving quality of life (SMD = 0.20 [0.08, 0.32]; P < 0.0001), walking speed (SMD = 0.26 [0.05, 0.48]; P = 0.005), balance ability (SMD = 0.23 [0.10, 0.36]; P < 0.0001), finger dexterity (SMD = 0.28 [0.10, 0.46]; P = 0.003) and decreasing fear of falling (SMD = -0.29 [-0.49, -0.08]; P = 0.001). However, home-based exercise did not significantly relieve the overall motor symptoms of PD patients when the training period was less than 8 weeks and the total number of sessions was less than 30.
During times of limited physical activity due to pandemics such as COVID-19, home-based exercise is an alternative to maintain and improve motor symptoms in PD patients. In addition, for the minimum dose of home-based exercise, we recommend that the exercise period is no less than 8 weeks and the total number of sessions is no less than 30 times.
PROSPERO registration number: CRD42022329780.
We performed a systematic review and meta-analysis, and searched PubMed, MEDLINE, Embase, Cochrane library, and Web of Science from their inception date to April 1, 2023. The quality of the literature was assessed using PEDro\'s quality scale. The data was pooled using R software. Results are presented as pooled standardized mean difference (SMD) with 95% confidence interval (CI).
A total of 20 studies involving 1885 PD patients were included. Meta-analysis results showed that home-based exercise had a small effect in relieving overall motor symptoms in PD patients (SMD = -0.29 [-0.45, -0.13]; P < 0.0001), improving quality of life (SMD = 0.20 [0.08, 0.32]; P < 0.0001), walking speed (SMD = 0.26 [0.05, 0.48]; P = 0.005), balance ability (SMD = 0.23 [0.10, 0.36]; P < 0.0001), finger dexterity (SMD = 0.28 [0.10, 0.46]; P = 0.003) and decreasing fear of falling (SMD = -0.29 [-0.49, -0.08]; P = 0.001). However, home-based exercise did not significantly relieve the overall motor symptoms of PD patients when the training period was less than 8 weeks and the total number of sessions was less than 30.
During times of limited physical activity due to pandemics such as COVID-19, home-based exercise is an alternative to maintain and improve motor symptoms in PD patients. In addition, for the minimum dose of home-based exercise, we recommend that the exercise period is no less than 8 weeks and the total number of sessions is no less than 30 times.
PROSPERO registration number: CRD42022329780.
摘要：
背景：面对特殊时期强制性家庭隔离造成的缺乏体力活动以及患者在进行专业监督下的锻炼时的不便，已经开发了许多基于家庭的锻炼计划。本系统综述和荟萃分析旨在研究家庭锻炼对运动症状测量的影响。帕金森病（PD）患者的生活质量和功能表现。
方法：我们进行了系统评价和荟萃分析，搜索PubMed,MEDLINE,Embase,科克伦图书馆,和WebofScience从成立日期到2023年4月1日。使用PEDro的质量量表评估文献的质量。使用R软件汇集数据。结果表示为具有95%置信区间(CI)的合并标准化平均差(SMD)。
结果：共纳入20项研究，涉及1885例PD患者。Meta分析结果显示,家庭运动对PD患者整体运动症状的缓解作用较小(SMD=-0.29[-0.45,-0.13];P<0.0001),改善生活质量（SMD=0.20[0.08，0.32]；P<0.0001），步行速度（SMD=0.26[0.05，0.48]；P=0.005），平衡能力(SMD=0.23[0.10，0.36]；P<0.0001)，手指灵巧(SMD=0.28[0.10,0.46];P=0.003)和下降的恐惧(SMD=-0.29[-0.49,-0.08];P=0.001)。然而,当训练期少于8周且总训练次数少于30周时,家庭锻炼并不能显著缓解PD患者的整体运动症状.
结论：在COVID-19等大流行导致体力活动受限的时期，家庭锻炼是维持和改善PD患者运动症状的一种替代方法。此外,以家庭为基础的运动的最小剂量，我们建议锻炼时间不少于8周，总次数不少于30次。
背景：PROSPERO注册号：CRD42022329780。
方法：我们进行了系统评价和荟萃分析，搜索PubMed,MEDLINE,Embase,科克伦图书馆,和WebofScience从成立日期到2023年4月1日。使用PEDro的质量量表评估文献的质量。使用R软件汇集数据。结果表示为具有95%置信区间(CI)的合并标准化平均差(SMD)。
结果：共纳入20项研究，涉及1885例PD患者。Meta分析结果显示,家庭运动对PD患者整体运动症状的缓解作用较小(SMD=-0.29[-0.45,-0.13];P<0.0001),改善生活质量（SMD=0.20[0.08，0.32]；P<0.0001），步行速度（SMD=0.26[0.05，0.48]；P=0.005），平衡能力(SMD=0.23[0.10，0.36]；P<0.0001)，手指灵巧(SMD=0.28[0.10,0.46];P=0.003)和下降的恐惧(SMD=-0.29[-0.49,-0.08];P=0.001)。然而,当训练期少于8周且总训练次数少于30周时,家庭锻炼并不能显著缓解PD患者的整体运动症状.
结论：在COVID-19等大流行导致体力活动受限的时期，家庭锻炼是维持和改善PD患者运动症状的一种替代方法。此外,以家庭为基础的运动的最小剂量，我们建议锻炼时间不少于8周，总次数不少于30次。
背景：PROSPERO注册号：CRD42022329780。
