PDF(Pubmed)
Abstract：
UNASSIGNED: Gastric cancer is one of the most common cancers worldwide and is the third most common cause of cancer related death. Improving postoperative results by understanding risk factors which impact outcomes is important. The current study aimed to compare immediate perioperative outcomes following gastrectomy.
UNASSIGNED: 302 patients following gastric resections over a 10-year period (January 2009-January 2020) were identified in a database and retrospectively analysed. Epidemiological as well as perioperative data was analysed, and a univariate and multivariate analysis performed to identify risk factors for in-hospital mortality.
UNASSIGNED: In general, gastrectomies were mainly performed electively (total vs. subtotal 95% vs. 85%, p = 0.004). Patients having subtotal gastrectomy needed significantly more PRBC transfusions compared to total gastrectomy (p = 0.039). Most emergency surgeries were performed for benign diseases, such as ulcer perforations or bleeding and gastric ischaemia. Only emergency surgery was significantly associated with poorer overall survival (HR 2.68, 95% CI 1.32-5.05, p = 0.003).
UNASSIGNED: In-hospital mortality was comparable between total and subtotal gastrectomies. Only emergency interventions increased postoperative fatality risk.
UNASSIGNED: 302 patients following gastric resections over a 10-year period (January 2009-January 2020) were identified in a database and retrospectively analysed. Epidemiological as well as perioperative data was analysed, and a univariate and multivariate analysis performed to identify risk factors for in-hospital mortality.
UNASSIGNED: In general, gastrectomies were mainly performed electively (total vs. subtotal 95% vs. 85%, p = 0.004). Patients having subtotal gastrectomy needed significantly more PRBC transfusions compared to total gastrectomy (p = 0.039). Most emergency surgeries were performed for benign diseases, such as ulcer perforations or bleeding and gastric ischaemia. Only emergency surgery was significantly associated with poorer overall survival (HR 2.68, 95% CI 1.32-5.05, p = 0.003).
UNASSIGNED: In-hospital mortality was comparable between total and subtotal gastrectomies. Only emergency interventions increased postoperative fatality risk.
摘要：
■胃癌是全球最常见的癌症之一，是癌症相关死亡的第三大常见原因。通过了解影响结果的危险因素来改善术后结果很重要。本研究旨在比较胃切除术后的围手术期近期结局。
■在10年期间（2009年1月至2020年1月）胃切除术后的302例患者在数据库中进行了鉴定并进行了回顾性分析。分析了流行病学和围手术期数据，进行单因素和多因素分析以确定院内死亡的危险因素.
■一般来说，胃切除术主要是选择性进行(总与小计95%与85%,p=0.004)。与全胃切除术相比，胃大部切除术的患者需要更多的PRBC输血（p=0.039）。大多数紧急手术是针对良性疾病进行的，如溃疡穿孔或出血和胃缺血。仅急诊手术与较差的总生存率显着相关（HR2.68，95％CI1.32-5.05，p=0.003）。
■全胃切除术和次全胃切除术的住院死亡率相当。只有紧急干预才会增加术后死亡风险。
■在10年期间（2009年1月至2020年1月）胃切除术后的302例患者在数据库中进行了鉴定并进行了回顾性分析。分析了流行病学和围手术期数据，进行单因素和多因素分析以确定院内死亡的危险因素.
■一般来说，胃切除术主要是选择性进行(总与小计95%与85%,p=0.004)。与全胃切除术相比，胃大部切除术的患者需要更多的PRBC输血（p=0.039）。大多数紧急手术是针对良性疾病进行的，如溃疡穿孔或出血和胃缺血。仅急诊手术与较差的总生存率显着相关（HR2.68，95％CI1.32-5.05，p=0.003）。
■全胃切除术和次全胃切除术的住院死亡率相当。只有紧急干预才会增加术后死亡风险。
