PDF(Pubmed)
Abstract：
Pulmonary disease caused by Mycobacterium abscessus is difficult to treat, as there is currently no reliable evidence-based treatment. Treatment is long, complex and has many side effects. In this case, we report a patient with treatment-refractory pulmonary M abscessus disease, treated with inhaled tigecycline. Treatment with inhaled tigecycline lasted 15 months with comparably limited side effects. There were no positive mycobacterial cultures in the follow-up period of 2 years. Inhaled tigecycline is an option in the treatment of pulmonary M. abscessus when first-line treatment fails. Additional research should investigate this further.
摘要：
由脓肿分枝杆菌引起的肺部疾病难以治疗，因为目前没有可靠的循证治疗。治疗时间长,复杂，有很多副作用。在这种情况下,我们报告了一名患有难治性肺脓肿M型疾病的患者，吸入替加环素治疗。吸入替加环素治疗持续15个月，副作用相对有限。在2年的随访期内，没有阳性的分枝杆菌培养。当一线治疗失败时，吸入替加环素是治疗肺脓肿分枝杆菌的一种选择。其他研究应该对此进行进一步调查。
