METHODS: The study sample comprised 60 adult patients (33 women and 27 men, aged between 18 and 60 years). Subjects were divided into 3 sagittal and vertical skeletal groups. CBCT images were segmented, mirrored and voxel-based registered with reference landmarks using ITK-SNAP® and 3DSlicer® software\'s. 3D surface models were constructed to evaluate the degree of asymmetry at different anatomical levels.
RESULTS: There was a degree of asymmetry, with the left hemimandible tending to contain the right one (0.123 ± 0.270 mm (CI95% 0.036-0.222; p < 0.001). Although the subjects under study did not present significant differences between mandibular asymmetries and their sagittal or vertical skeletal pattern (p = 0.809 and p = 0.453, respectively), a statistically significant difference has been found depending on the anatomical region (p < 0.001; CI95%=1.020-1.021), being higher in the condyle, followed by the ramus and the corpus.
CONCLUSIONS: Although mandibular asymmetries cannot be correlated with vertical and sagittal skeletal patterns in symmetric patients, knowledge about 3D segmentation procedures and color maps can provide valuable information to identify mandibular asymmetries.
方法:研究样本包括60名成年患者(33名女性和27名男性,年龄在18至60岁之间)。受试者分为3个矢状和垂直骨骼组。CBCT图像被分割,使用ITK-SNAP®和3DSlicer®软件与参考地标进行镜像和基于体素的配准。构建3D表面模型以评估不同解剖水平的不对称程度。
结果:存在一定程度的不对称性,左侧半可食倾向于包含右侧(0.123±0.270mm(CI95%0.036-0.222;p<0.001)。尽管所研究的受试者在下颌不对称性及其矢状或垂直骨骼模式之间没有显着差异(分别为p=0.809和p=0.453),根据解剖区域发现了统计学上的显着差异(p<0.001;CI95%=1.020-1.021),髁更高,其次是ramus和语料库。
结论:尽管在对称患者中下颌不对称性与垂直和矢状骨骼模式不能相关,有关3D分割程序和彩色图的知识可以提供有价值的信息来识别下颌不对称。