Abstract：
Valsalva maneuver (VM) is a technique widely used for acute elevation of blood pressure in humans. It has potential applications in cardiac health prediction and is also a diagnostic tool in cardiovascular, neurology and ENT screening. The jugular venous (JV) diameter increases during the VM procedure and hence it has been widely used to aid central venous catheterization in medical units. In this pilot study, we have quantified the variation in JV diameter response to VM across young and middle-aged populations. The study was conducted on a cohort of 16 males and 11 females, where the JV diameter in baseline, during and post VM intervention were acquired using a B-mode imaging system. The JV diameter measurements were within the ranges specified in earlier literature. The beat-to-beat variability in baseline diameter measurements was found to be between 8% to 20%. In younger population, the average maximum JV diameter during baseline was found to be 9.25 ± 2.61 mm and in middle-aged population it was 12.49 ± 2.65 mm. The average maximum JV diameter in young and middle-aged population during VM was 11.66 ± 2.74 mm and 16.73 ± 3.28 mm respectively. The study findings suggested a statistically significant variation (p < 0.05) between the JV diameter responses from young and middle-aged populations. The JV distensibility decreased significantly during VM in younger cohort (-35%) in comparison with the minimal changes observed in middle-aged population. The study demonstrates the variation in JV diameter and distensibility to VM in young and middle-aged populations.Clinical Relevance- This pilot study reveals the variations in JV diameter in response to VM intervention in young and middle-aged groups which has potential utility in assessing age dependent changes in vasculature.
摘要：
Valsalva机动（VM）是一种广泛用于人类急性血压升高的技术。它在心脏健康预测中具有潜在的应用，也是心血管疾病的诊断工具，神经病学和耳鼻喉科筛查。颈静脉（JV）直径在VM过程中增加，因此已被广泛用于医疗单位中的中心静脉导管插入。在这项试点研究中，我们已经量化了青年和中年人群对VM的JV直径反应的变化。这项研究是在16名男性和11名女性的队列中进行的，其中基线中的JV直径，使用B模式成像系统在VM干预期间和之后获得.JV直径测量值在早期文献中规定的范围内。发现基线直径测量中的逐次搏动变异性在8%至20%之间。在年轻人口中，基线时平均最大JV直径为9.25±2.61mm,中年人群为12.49±2.65mm.VM期间中青年人群的平均最大JV直径分别为11.66±2.74mm和16.73±3.28mm。研究结果表明，青年和中年人群的JV直径反应之间存在统计学上的显着差异（p<0.05）。与中年人群中观察到的最小变化相比，年轻队列中的VM期间的JV扩张性显着降低（-35％）。该研究表明，在青年和中年人群中，JV直径和对VM的扩张性存在差异。临床相关性-这项初步研究揭示了青年和中年群体对VM干预的反应中JV直径的变化，这在评估血管系统的年龄依赖性变化方面具有潜在的实用性。
