Abstract：
This brief picture-oriented case report focuses on typical skin lesions in a patient who developed Ecthyma gangrenosum and pseudomonal sepsis after extensive immunosuppressive therapy for Pemphigus vulgaris.
The patient was immunosuppressed with high doses of glucocorticoids and azathioprine; the follow-up after the treatment was not carried out well due to the pandemic conditions and because the patient herself got a Covid infection, which resulted in the development of pseudomonal sepsis and Ecthyma gangrenosum. The outcome was fatal despite extensive broad-spectrum antibiotic therapy, plasmapheresis, and intravenous immunoglobulins.
Infections with Pseudomonas aeruginosa have become a real concern in hospital-acquired infections, especially in critically ill and immunocompromised patients, because of multi-drug resistance in the first place.
The patient was immunosuppressed with high doses of glucocorticoids and azathioprine; the follow-up after the treatment was not carried out well due to the pandemic conditions and because the patient herself got a Covid infection, which resulted in the development of pseudomonal sepsis and Ecthyma gangrenosum. The outcome was fatal despite extensive broad-spectrum antibiotic therapy, plasmapheresis, and intravenous immunoglobulins.
Infections with Pseudomonas aeruginosa have become a real concern in hospital-acquired infections, especially in critically ill and immunocompromised patients, because of multi-drug resistance in the first place.
摘要：
背景：这篇简短的以图片为导向的病例报告集中于一名患者的典型皮肤病变，该患者在对寻常型天疱疮进行广泛的免疫抑制治疗后出现坏疽性坏疽和假性脓毒症。
方法：患者被高剂量糖皮质激素和硫唑嘌呤免疫抑制；由于大流行的情况，治疗后的随访没有很好地进行，因为患者自己感染了Covid，这导致了假性败血症和坏疽性坏疽的发展。结果是致命的，尽管广泛的广谱抗生素治疗，血浆置换,和静脉注射免疫球蛋白.
结论：铜绿假单胞菌感染已成为医院获得性感染的真正问题，尤其是在危重病和免疫功能低下的患者中，首先是因为多重耐药性。
方法：患者被高剂量糖皮质激素和硫唑嘌呤免疫抑制；由于大流行的情况，治疗后的随访没有很好地进行，因为患者自己感染了Covid，这导致了假性败血症和坏疽性坏疽的发展。结果是致命的，尽管广泛的广谱抗生素治疗，血浆置换,和静脉注射免疫球蛋白.
结论：铜绿假单胞菌感染已成为医院获得性感染的真正问题，尤其是在危重病和免疫功能低下的患者中，首先是因为多重耐药性。
