{Reference Type}: Case Reports
{Title}: A fatal case of Ecthyma Gangrenosum in a critically ill and immunocompromised patient.
{Author}: Tomanovic M;Reljic V;Peric J;Zivanovic D;
{Journal}: J Infect Dev Ctries
{Volume}: 17
{Issue}: 11
{Year}: 2023 11 30
{Factor}: 2.552
{DOI}: 10.3855/jidc.18040
{Abstract}: This brief picture-oriented case report focuses on typical skin lesions in a patient who developed Ecthyma gangrenosum and pseudomonal sepsis after extensive immunosuppressive therapy for Pemphigus vulgaris.<BR>The patient was immunosuppressed with high doses of glucocorticoids and azathioprine; the follow-up after the treatment was not carried out well due to the pandemic conditions and because the patient herself got a Covid infection, which resulted in the development of pseudomonal sepsis and Ecthyma gangrenosum. The outcome was fatal despite extensive broad-spectrum antibiotic therapy, plasmapheresis, and intravenous immunoglobulins.<BR>Infections with Pseudomonas aeruginosa have become a real concern in hospital-acquired infections, especially in critically ill and immunocompromised patients, because of multi-drug resistance in the first place.