关键词: Campylobacter culture techniques epidemiological monitoring foodborne diseases polymerase chain reaction public health surveillance

Mesh : Humans Campylobacter Infections / diagnosis epidemiology microbiology Retrospective Studies Campylobacter / genetics Gastroenteritis Denmark / epidemiology Polymerase Chain Reaction

来  源:   DOI:10.1128/spectrum.03418-23   PDF(Pubmed)

Abstract:
OBJECTIVE: This study is important because it shows the potential epidemiological silence associated with the use of culture as the primary diagnostic method for the laboratory identification of human campylobacteriosis. Also, we show how polymerase chain reaction methods are associated with a systematic increase in the number of human campylobacteriosis episodes as reported by routine disease surveillance. These findings are operationally relevant and have public health implications because they tell how crucial it is to consider changes in diagnostic methods, e.g., in the epidemiological analysis of historical data and in the interpretation of future data in light of the past. We also believe that this study highlights how the synergy between microbiology and epidemiology is essential for disease surveillance.
摘要:
目的:这项研究很重要,因为它显示了与使用培养作为实验室鉴定人类弯曲杆菌病的主要诊断方法相关的潜在流行病学沉默。此外,我们展示了聚合酶链反应方法如何与常规疾病监测报告的人类弯曲杆菌病发作次数系统性增加相关.这些发现与操作相关,并具有公共卫生意义,因为它们表明了考虑诊断方法变化的重要性。例如,在对历史数据的流行病学分析和根据过去对未来数据的解释中。我们还认为,这项研究强调了微生物学和流行病学之间的协同作用对于疾病监测至关重要。
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