METHODS: This cross-sectional study involved 231 women with CVF and 563 women without CVF aged 60-90 years who underwent dual-energy X-ray absorptiometry during 2019-2023. They were divided into osteoporosis, osteopenia, and normal groups according to bone mineral density of the lumbar spine. Reference values for TBS were defined as low (≤ 1.23), intermediate (1.23-1.31), and high (≥ 1.31).
RESULTS: Among patients without anti-osteoporosis treatment (n = 476), the proportion with low TBS was 36.7% in the CVF group and 10.7% in the control group. The proportion with CVF was higher in the low TBS group than in the intermediate and high TBS groups, especially in the osteoporosis group (p < 0.001). The odds ratio for CVF was higher in the low TBS group than in the intermediate and high especially in patients with normal BMD and osteoporosis. The TBS cut-off values for incidence of CVF in the osteoporosis, osteopenia, and normal groups were 1.224, 1.319, and 1.322, respectively.
CONCLUSIONS: The reference value for low TBS (≤ 1.23) was useful as an indicator for CVF, especially in patients with osteoporosis. It is expected that reference values for TBS will be established in official guidelines in the future.
方法:这项横断面研究涉及231名患有CVF的女性和563名年龄在60-90岁之间的无CVF的女性,他们在2019-2023年期间接受了双能X射线吸收测定法。它们分为骨质疏松症,骨质减少,根据腰椎的骨密度和正常组。TBS的参考值定义为低(≤1.23),中间(1.23-1.31),和高(≥1.31)。
结果:在没有抗骨质疏松治疗的患者中(n=476),CVF组低TBS的比例为36.7%,对照组为10.7%。低TBS组有CVF的比例高于中、高TBS组,尤其是骨质疏松组(p<0.001)。低TBS组的CVF比值比高于中,高,尤其是正常BMD和骨质疏松症的患者。骨质疏松症中CVF发生率的TBS临界值,骨质减少,和正常组分别为1.224、1.319和1.322。
结论:低TBS(≤1.23)的参考值可用作CVF的指标,尤其是骨质疏松症患者。预计将来将在官方准则中确定TBS的参考值。