Abstract：
The clinical findings associated with nasal, cutaneous and systemic fusariosis in a 3-year-old billy Boer goat are summarised. The clinical features, treatment, postmortem findings and laboratory diagnostics are reported and discussed in the context of existing knowledge on mycoses of small ruminants. The goat presented primarily for respiratory signs (inspiratory dyspnoea) with unilateral left-sided mucopurulent nasal discharge, and multifocal variably ulcerative and necrotic cutaneous nodules. Histopathology of nasal and cutaneous biopsies revealed necrotising pyogranulomatous inflammation with intralesional septate hyphal elements that correlated with culture of Fusarium oxysporum. The patient continued to deteriorate clinically during treatment with oxytetracycline and meloxicam, with the addition of sodium iodide and potassium iodide, and was humanely euthanased. Postmortem examination revealed multifocal nodular lesions throughout the kidneys, abdominal lymph nodes and lungs. These lesions were consistent with those identified antemortem from which F. oxysporum was cultured. Although treatment was unsuccessful, to the author\'s knowledge, no instance of rhinofacial or systemic caprine infection with Fusarium spp. has been documented in the veterinary literature, making this the first recognised instance of this form of infection in small ruminant species.
摘要：
与鼻相关的临床表现，总结了3岁的比利布尔山羊的皮肤和全身性镰刀菌病。临床特征，治疗,在小反刍动物真菌病的现有知识的背景下，报告和讨论了验尸结果和实验室诊断。山羊主要表现为呼吸体征（吸气性呼吸困难），伴有单侧左侧粘液脓性鼻腔分泌物，多灶性可变溃疡性和坏死性皮肤结节。鼻和皮肤活检的组织病理学显示，坏死性脓性肉芽肿性炎症伴有与尖孢镰刀菌培养相关的病灶内间隔菌丝元素。患者在使用土霉素和美洛昔康治疗期间继续临床恶化，加入碘化钠和碘化钾，被人道地安乐死。尸检显示整个肾脏有多灶性结节性病变，腹部淋巴结和肺。这些病变与培养尖孢酵母的生前鉴定的病变一致。虽然治疗不成功,根据作者的知识，没有镰刀菌属的鼻面部或全身性山羊感染的实例。已经记录在兽医文献中，使其成为小反刍动物物种中这种感染形式的第一个公认实例。
