PDF(Pubmed)
Abstract：
BACKGROUND: The pathological examination of a medicolegal autopsy is a great learning opportunity for a pathologist as well as for a forensic expert, where the cause of death remains unknown. Liver disease epidemiology differs from one geographic area to another.
METHODS: This was a prospective observational study with 100 medicolegal autopsy cases over a one-year period conducted in the Department of Forensic Medicine and Toxicology (FMT) and Pathology. Representative tissue from the liver was collected in 10% neutral buffered formalin and sent for histopathological examination.
RESULTS: The mean age of the cases was 41.98 ± 15.39 years, and ages ranged from 20 to 90 years with male preponderance. The most common histopathology and gross findings noted were mild to moderate chronic hepatitis (CH) (54%) and fatty change (36%), respectively. There was a significant association (p ≤ 0.05) between histopathology and gross findings, cause, and manner of death.
CONCLUSIONS: Gross and histopathological examination of the liver in a medicolegal autopsy has a significant role in ascertaining the cause and manner of death.
METHODS: This was a prospective observational study with 100 medicolegal autopsy cases over a one-year period conducted in the Department of Forensic Medicine and Toxicology (FMT) and Pathology. Representative tissue from the liver was collected in 10% neutral buffered formalin and sent for histopathological examination.
RESULTS: The mean age of the cases was 41.98 ± 15.39 years, and ages ranged from 20 to 90 years with male preponderance. The most common histopathology and gross findings noted were mild to moderate chronic hepatitis (CH) (54%) and fatty change (36%), respectively. There was a significant association (p ≤ 0.05) between histopathology and gross findings, cause, and manner of death.
CONCLUSIONS: Gross and histopathological examination of the liver in a medicolegal autopsy has a significant role in ascertaining the cause and manner of death.
摘要：
背景：法医学尸检的病理检查对于病理学家和法医专家来说都是一个很好的学习机会，死因不明.肝病流行病学因地理区域而异。
方法：这是一项前瞻性观察性研究，在法医学和毒理学（FMT）和病理学系进行了为期一年的100例法医学尸检病例。将来自肝脏的代表性组织收集在10%中性缓冲的福尔马林中并送去进行组织病理学检查。
结果：病例平均年龄为41.98±15.39岁，年龄从20岁到90岁不等，男性占优势。最常见的组织病理学和总体发现是轻度至中度慢性肝炎（CH）（54％）和脂肪变化（36％），分别。组织病理学和总体结果之间存在显着关联（p≤0.05），cause,和死亡的方式。
结论：医学尸检中肝脏的大体和组织病理学检查在确定死亡原因和方式方面具有重要作用。
方法：这是一项前瞻性观察性研究，在法医学和毒理学（FMT）和病理学系进行了为期一年的100例法医学尸检病例。将来自肝脏的代表性组织收集在10%中性缓冲的福尔马林中并送去进行组织病理学检查。
结果：病例平均年龄为41.98±15.39岁，年龄从20岁到90岁不等，男性占优势。最常见的组织病理学和总体发现是轻度至中度慢性肝炎（CH）（54％）和脂肪变化（36％），分别。组织病理学和总体结果之间存在显着关联（p≤0.05），cause,和死亡的方式。
结论：医学尸检中肝脏的大体和组织病理学检查在确定死亡原因和方式方面具有重要作用。
