Abstract:
Self-monitoring in tumor therapy is a concept that allows for real-time monitoring of the location and state of applied nanomaterials. This monitoring relies on dynamic signals, such as wave or magnetic signals, which vary in response to changes in the location and state of nanomaterials. Dynamic changes in nanomaterials can be monitored using dynamic signals, making it possible to determine and control the treatment process. Theranostic nanomaterials, which possess unique physical and chemical properties, have recently been explored as a viable option for self-monitoring. With the help of self-monitoring, theranostic nanomaterials can guide themselves to achieve region-selective treatment with higher controllability and safety. In this review, self-monitoring theranostic nanomaterials will be introduced in three parts according to their roles during therapy: tumor accumulation, tumor therapy, and metabolism. The limitations and future challenges of current self-monitoring theranostic nanomaterials will also be discussed.
摘要:
肿瘤治疗中的自我监测是一个概念,可以实时监测所应用的纳米材料的位置和状态。这种监测依赖于动态信号,如波或磁信号,随着纳米材料位置和状态的变化而变化。可以使用动态信号监测纳米材料的动态变化,可以确定和控制处理过程。Theranostic纳米材料,具有独特的物理和化学性质,最近被探索为自我监控的可行选择。在自我监控的帮助下,theranostic纳米材料可以指导自己实现区域选择性治疗,具有更高的可控性和安全性。在这次审查中,自我监测治疗纳米材料将根据其在治疗过程中的作用分为三个部分:肿瘤积聚,肿瘤治疗,和新陈代谢。还将讨论当前自我监测的恒温纳米材料的局限性和未来挑战。