Abstract：
OBJECTIVE: To determine the role of surgery of the primary tumor site in the management of primary major salivary gland cancer.
METHODS: The French Network of Rare Head and Neck Tumors (REFCOR) formed a steering group, which drafted a non-systematic narrative review of the literature published on Medline, and proposed recommendations. The level of adherence to the recommendations was then assessed by a rating group, according to the formal consensus method.
RESULTS: Treatment of salivary gland tumor is mainly surgical. The gold standard for parotid cancer is a total parotidectomy, to obtain clear margins and remove all intraparotid lymph nodes. For low-grade tumors, partial parotidectomy with wide excision of the tumor is acceptable in the case of postoperative diagnosis on definitive histology. In the event of positive margins on definitive analysis, revision surgery should be assessed for feasibility, and performed if possible.
CONCLUSIONS: Treatment of primary major salivary gland cancer is based on surgery with clear resection margins, as far away as possible from the tumor. The type of surgery depends on tumor location, pathologic type and extension.
METHODS: The French Network of Rare Head and Neck Tumors (REFCOR) formed a steering group, which drafted a non-systematic narrative review of the literature published on Medline, and proposed recommendations. The level of adherence to the recommendations was then assessed by a rating group, according to the formal consensus method.
RESULTS: Treatment of salivary gland tumor is mainly surgical. The gold standard for parotid cancer is a total parotidectomy, to obtain clear margins and remove all intraparotid lymph nodes. For low-grade tumors, partial parotidectomy with wide excision of the tumor is acceptable in the case of postoperative diagnosis on definitive histology. In the event of positive margins on definitive analysis, revision surgery should be assessed for feasibility, and performed if possible.
CONCLUSIONS: Treatment of primary major salivary gland cancer is based on surgery with clear resection margins, as far away as possible from the tumor. The type of surgery depends on tumor location, pathologic type and extension.
摘要：
目的：确定原发肿瘤部位手术在原发涎腺癌治疗中的作用。
方法：法国罕见头颈部肿瘤网络（REFCOR）组成了一个指导小组，对Medline上发表的文献进行了非系统的叙事综述，并提出建议。然后由评级小组评估对建议的遵守程度，根据正式共识方法。
结果：涎腺肿瘤的治疗主要是手术治疗。腮腺癌的黄金标准是全腮腺切除术，获得清晰的边缘并切除所有的腮腺内淋巴结。对于低度肿瘤，在明确组织学的术后诊断的情况下，腮腺部分切除术和肿瘤的广泛切除是可以接受的。如果确定性分析的利润率为正，应评估翻修手术的可行性，并在可能的情况下进行。
结论：原发性大涎腺癌的治疗是基于手术切除边缘清晰，尽可能远离肿瘤。手术类型取决于肿瘤的位置,病理类型和延伸。
方法：法国罕见头颈部肿瘤网络（REFCOR）组成了一个指导小组，对Medline上发表的文献进行了非系统的叙事综述，并提出建议。然后由评级小组评估对建议的遵守程度，根据正式共识方法。
结果：涎腺肿瘤的治疗主要是手术治疗。腮腺癌的黄金标准是全腮腺切除术，获得清晰的边缘并切除所有的腮腺内淋巴结。对于低度肿瘤，在明确组织学的术后诊断的情况下，腮腺部分切除术和肿瘤的广泛切除是可以接受的。如果确定性分析的利润率为正，应评估翻修手术的可行性，并在可能的情况下进行。
结论：原发性大涎腺癌的治疗是基于手术切除边缘清晰，尽可能远离肿瘤。手术类型取决于肿瘤的位置,病理类型和延伸。
