Abstract:
Effective drug distribution at the intended or particular location is a critical issue that researchers are now dealing. Nanosponges have significantly increased in importance in medication delivery using nanotechnology in recent years. An important step toward solving these problems has been the development of nanosponges. Recently created and proposed for use in drug delivery, nanosponge is a unique type of hyper-crosslinked polymer-based colloidal structures made up of solid nanoparticles with colloidal carriers. Nanosponges are solid porous particles that may hold pharmaceuticals and other actives in their nanocavities. They can be made into dosage forms for oral, parenteral, topical, or inhalation use. The targeted distribution of drugs in a regulated manner is greatly aided by nanosponge. The utilization of nanosponges, their benefits, their production processes, the polymers they are made of, and their characterization have all been covered in this review article.
摘要:
在预期或特定位置的有效药物分配是研究人员现在正在处理的关键问题。近年来,纳米海绵在使用纳米技术的药物递送中的重要性显著增加。解决这些问题的一个重要步骤是开发纳米海绵。最近创建并提议用于药物输送,纳米海绵是一种独特的超交联聚合物基胶体结构,由固体纳米颗粒和胶体载体组成。纳米海绵是固体多孔颗粒,其可以将药物和其他活性物质保持在其纳米腔中。它们可以制成口服剂型,肠胃外,topic,或吸入使用。纳米海绵极大地帮助了药物以受调节的方式靶向分布。纳米海绵的利用,他们的好处,他们的生产过程,它们组成的聚合物,以及它们的表征都在这篇综述文章中进行了介绍。