UNASSIGNED: The National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018 was used to extract a series of variables for participants who took the stroke questionnaire. The construction of OBS relied on diet and lifestyle components, which included 16 nutrients and 4 lifestyle factors. Weighted multivariable-adjusted logistic regression was performed to investigate the association between stroke risk and OBS. A stratified analysis was also conducted. The dose-response relationship between stroke risk and OBS was elucidated by performing a restricted cubic spline function.
UNASSIGNED: A total of 20,680 participants were included for analysis, 768 of whom suffered from stroke. Based on weighted multivariable logistic regression analysis, we discovered that the stroke prevalence decreased by 2% for each OBS unit added [OR: 0.98 (0.97-1.00), P < 0.01]. For the OBS subgroup, we also discovered that higher OBS was related to a reduction in the risk of stroke [Q4 vs. Q1: OR:0.65 (0.46-0.90), P < 0.01]. The prevalence of stroke declined by 3% with every OBS unit added to the diet component [OR: 0.97 (0.96-0.99), P < 0.01]. For the dietary OBS subgroup, higher OBS in diet components was associated with a decrease in the prevalence of stroke [Q4 vs. Q1: OR: 0.65, (0.47-0.91), P < 0.05]. Further stratified analysis showed that every OBS unit raised was associated with a decline in stroke prevalence, which was statistically significant in participants in subgroups of ≥60 years, female, no-diabetes mellitus and no-hypertension. OBS and stroke prevalence were correlated in a linear manner.
UNASSIGNED: The study found that a higher OBS was associated with a decrease in stroke prevalence, which could be a significant indicator for evaluating stroke risk.
■使用1999年至2018年的国家健康与营养检查调查(NHANES)为参加中风问卷的参与者提取了一系列变量。OBS的建设依赖于饮食和生活方式的组成部分,其中包括16种营养素和4种生活方式因素。采用加权多变量调整逻辑回归分析卒中风险与OBS之间的关系。还进行了分层分析。卒中风险与OBS之间的剂量反应关系通过执行有限的三次样条函数来阐明。
■总共20,680名参与者被纳入分析,其中768人患有中风。基于加权多变量逻辑回归分析,我们发现,每增加一个OBS单位的卒中患病率下降2%[OR:0.98(0.97-1.00),P<0.01]。对于OBS子组,我们还发现,较高的OBS与卒中风险降低有关[第4季度与Q1:或:0.65(0.46-0.90),P<0.01]。在饮食中添加每个OBS单位,中风的患病率下降了3%[OR:0.97(0.96-0.99),P<0.01]。对于饮食OBS亚组,饮食成分中OBS升高与卒中患病率降低相关[Q4与Q1:或:0.65,(0.47-0.91),P<0.05]。进一步的分层分析显示,每增加一个OBS单位与卒中患病率下降有关,这在≥60岁的亚组中具有统计学意义,女性,无糖尿病和无高血压。OBS与卒中患病率呈线性关系。
■研究发现,OBS升高与卒中患病率下降有关,这可能是评估中风风险的重要指标。