PDF(Pubmed)
Abstract：
UNASSIGNED: Present the results of the secondary obliteration of chronically discharging radical cavities using S53P4 bioactive glass (BAG).
UNASSIGNED: Retrospective cohort study.
UNASSIGNED: Single-center study.
UNASSIGNED: A single-center retrospective cohort study was conducted of all patients that underwent secondary obliteration of persistently draining radical cavities using S53P4 BAG between 2011 and 2022. Patients with middle ear cholesteatoma were excluded. The main outcome was postoperative otorrhea, as indicated by Merchant grading.
UNASSIGNED: In total, 97 patients were included. The median postoperative follow-up time was 3.9 years (range 0.5-10.4). Average time between the original canal wall down surgery and the secondary obliteration was 25.3 years (SD 11.7, range 2-66). At the most recent follow-up visit, a Merchant grade of 0 to 1 was observed in 95% of the cases. There were no cases of sensorineural hearing loss or facial palsy, one case developed a retro auricular skin defect and 1 patient developed CSF leakage. Minor complications were seen in 10 patients (10%). Ossicular chain reconstruction with a titanium prosthesis was performed in 42 cases, resulting in a median improvement of 11.2 dB in air conduction thresholds. In 9/42 cases (21%), closure of the postoperative air-bone gap to ≤20 dB was achieved. Twenty-five percent of cases could be discharged from out-patient visits.
UNASSIGNED: Revision of persistently draining radical cavities with BAG obliteration is feasible and results in a dry and safe ear in 95% of the patients, thereby enabling wearing of a conventional hearing aid. Out-patient visits could be ceased in 25% of the cases.
UNASSIGNED: Retrospective cohort study.
UNASSIGNED: Single-center study.
UNASSIGNED: A single-center retrospective cohort study was conducted of all patients that underwent secondary obliteration of persistently draining radical cavities using S53P4 BAG between 2011 and 2022. Patients with middle ear cholesteatoma were excluded. The main outcome was postoperative otorrhea, as indicated by Merchant grading.
UNASSIGNED: In total, 97 patients were included. The median postoperative follow-up time was 3.9 years (range 0.5-10.4). Average time between the original canal wall down surgery and the secondary obliteration was 25.3 years (SD 11.7, range 2-66). At the most recent follow-up visit, a Merchant grade of 0 to 1 was observed in 95% of the cases. There were no cases of sensorineural hearing loss or facial palsy, one case developed a retro auricular skin defect and 1 patient developed CSF leakage. Minor complications were seen in 10 patients (10%). Ossicular chain reconstruction with a titanium prosthesis was performed in 42 cases, resulting in a median improvement of 11.2 dB in air conduction thresholds. In 9/42 cases (21%), closure of the postoperative air-bone gap to ≤20 dB was achieved. Twenty-five percent of cases could be discharged from out-patient visits.
UNASSIGNED: Revision of persistently draining radical cavities with BAG obliteration is feasible and results in a dry and safe ear in 95% of the patients, thereby enabling wearing of a conventional hearing aid. Out-patient visits could be ceased in 25% of the cases.
摘要：
■呈现使用S53P4生物活性玻璃（BAG）对慢性放电自由基腔进行二次消除的结果。
■回顾性队列研究。
■单中心研究。
■在2011年至2022年间，对所有使用S53P4BAG的持续引流根治性空洞进行二次闭塞的患者进行了一项单中心回顾性队列研究。排除中耳胆脂瘤患者。主要结果是术后耳漏，如商户分级所示。
■总共，包括97名患者。术后中位随访时间为3.9年（范围0.5-10.4）。原始管壁向下手术与二次闭塞之间的平均时间为25.3年（SD11.7，范围2-66）。在最近的后续访问中，在95%的病例中观察到0到1的商人等级。没有感觉神经性听力损失或面部麻痹的病例，1例出现耳廓皮肤缺损，1例出现脑脊液漏。10例患者（10％）出现轻微并发症。用钛假体进行听骨链重建42例，导致空气传导阈值中位数提高11.2dB。在9/42例（21%）中，术后气骨间隙闭合至≤20dB。25％的病例可以从门诊就诊中出院。
■用BAG闭塞术对持续引流的根腔进行修正是可行的，并导致95％的患者耳干而安全，从而能够佩戴传统的助听器。25%的病例可以停止门诊就诊。
■回顾性队列研究。
■单中心研究。
■在2011年至2022年间，对所有使用S53P4BAG的持续引流根治性空洞进行二次闭塞的患者进行了一项单中心回顾性队列研究。排除中耳胆脂瘤患者。主要结果是术后耳漏，如商户分级所示。
■总共，包括97名患者。术后中位随访时间为3.9年（范围0.5-10.4）。原始管壁向下手术与二次闭塞之间的平均时间为25.3年（SD11.7，范围2-66）。在最近的后续访问中，在95%的病例中观察到0到1的商人等级。没有感觉神经性听力损失或面部麻痹的病例，1例出现耳廓皮肤缺损，1例出现脑脊液漏。10例患者（10％）出现轻微并发症。用钛假体进行听骨链重建42例，导致空气传导阈值中位数提高11.2dB。在9/42例（21%）中，术后气骨间隙闭合至≤20dB。25％的病例可以从门诊就诊中出院。
■用BAG闭塞术对持续引流的根腔进行修正是可行的，并导致95％的患者耳干而安全，从而能够佩戴传统的助听器。25%的病例可以停止门诊就诊。
