PDF(Pubmed)
Abstract：
Mycotoxins are toxic compounds that pose a serious threat to animal health and food safety. Therefore, there is an urgent need for safe and efficient methods of detoxifying mycotoxins. As biotechnology has continued to develop, methods involving biological enzymes have shown great promise. Biological enzymatic methods, which can fundamentally destroy the structures of mycotoxins and produce degradation products whose toxicity is greatly reduced, are generally more specific, efficient, and environmentally friendly. Mycotoxin-degrading enzymes can thus facilitate the safe and effective detoxification of mycotoxins which gives them a huge advantage over other methods. This article summarizes the newly discovered degrading enzymes that can degrade four common mycotoxins (aflatoxins, zearalenone, deoxynivalenol, and ochratoxin A) in the past five years, and reveals the degradation mechanism of degrading enzymes on four mycotoxins, as well as their positive effects on animal production. This review will provide a theoretical basis for the safe treatment of mycotoxins by using biological enzyme technology.
摘要：
霉菌毒素是对动物健康和食品安全构成严重威胁的有毒化合物。因此,迫切需要安全有效的真菌毒素解毒方法。随着生物技术的不断发展，涉及生物酶的方法显示出巨大的前景。生物酶学方法,可以从根本上破坏霉菌毒素的结构，产生毒性大大降低的降解产物，通常更具体，高效,和环保。因此,霉菌毒素降解酶可以促进霉菌毒素的安全和有效的解毒,这使它们比其他方法具有巨大的优势。本文总结了新发现的降解酶，可以降解四种常见的真菌毒素（黄曲霉毒素，玉米赤霉烯酮,脱氧雪腐镰刀菌烯醇,和曲霉毒素A）在过去的五年中，并揭示了降解酶对四种真菌毒素的降解机理，以及它们对动物生产的积极影响。本综述将为利用生物酶技术安全治疗真菌毒素提供理论依据。
