PDF(Pubmed)
Abstract：
Two dogs presented with bilateral pattern-forming corneal opacity. Treatment with topical immunosuppressants was initiated after a complete ophthalmic examination. The response to treatment was assessed by analyzing serial images using slit-lamp biomicroscopy and spectral domain optical coherence tomography (SD-OCT). Both dogs responded to topical immunosuppressants; however, the lesions recurred once the treatment was abated or withdrawn. The most effective immunosuppressant in both dogs was 0.03% tacrolimus ointment. Early and continuous treatment with topical immunosuppressants may be necessary to improve corneal clarity and prevent scarring. SD-OCT could provide useful structural information regarding presumed immune-mediated keratitis and aid in monitoring treatment response.
摘要：
两只狗表现为双侧图案形成的角膜混浊。在完整的眼科检查后，开始使用局部免疫抑制剂进行治疗。通过使用裂隙灯生物显微镜和光谱域光学相干断层扫描（SD-OCT）分析系列图像来评估对治疗的反应。两只狗都对局部免疫抑制剂有反应；然而，一旦治疗减轻或停止，病变就会复发。两只狗中最有效的免疫抑制剂是0.03％他克莫司软膏。早期和连续治疗局部免疫抑制剂可能是必要的，以提高角膜透明度和防止疤痕。SD-OCT可以提供有关假定的免疫介导性角膜炎的有用结构信息，并有助于监测治疗反应。
