关键词: asthma chronic bronchitis emphysema smoking

Mesh : Humans Male Female Pulmonary Disease, Chronic Obstructive / diagnosis epidemiology complications Case-Control Studies Forced Expiratory Volume Vital Capacity Uganda Risk Factors Spirometry

来  源:   DOI:10.2147/COPD.S426928   PDF(Pubmed)

Abstract:
UNASSIGNED: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. In this paper, we determined risk factors for COPD among patients presenting to pulmonology and medical outpatients\' clinics of Mbarara Regional Referral Hospital (MRRH).
UNASSIGNED: In this case-control study, cases were patients with COPD confirmed by spirometry and controls were those with normal spirometry. The two groups were matched by age and gender.
UNASSIGNED: We enrolled 123 participants, of whom 41 were cases and 82 controls. A total of 51 women (41.5%) and 72 men (58.5%), of whom 25 were male cases (61%) and 47 were male controls (57%), were included. The results of our study suggest that the variables associated with the presence of COPD among participants attending MRRH were a history of having ever smoked and a prior history of atopy. This brings to our attention the fact that smoking remains a major risk factor for COPD in this setting, just as it is in developed countries.
UNASSIGNED: Our study has shown that the factors associated with COPD are smoking and a history of atopy. Patients with a history of asthma and tuberculosis are also probably more likely to develop COPD than those without similar disease conditions.
摘要:
慢性阻塞性肺疾病(COPD)是全球发病率和死亡率的主要原因。在本文中,我们在Mbarara地区转诊医院(MRRH)肺科和门诊就诊的患者中确定了COPD的危险因素.
在本病例对照研究中,病例为肺活量测定证实的COPD患者,对照组为肺活量测定正常的患者。两组患者年龄、性别匹配。
我们注册了123名参与者,其中41例为病例,82例为对照。共有51名女性(41.5%)和72名男性(58.5%),其中25例为男性(61%),47例为男性对照(57%),包括在内。我们的研究结果表明,参加MRRH的参与者中与COPD存在相关的变量是曾经吸烟的历史和以前的特应性病史。这引起了我们的注意,在这种情况下,吸烟仍然是COPD的主要危险因素,就像在发达国家一样。
我们的研究表明,与COPD相关的因素是吸烟和特应性病史。有哮喘和结核病史的患者也可能比没有类似疾病的患者更容易发展为COPD。
公众号