关键词: case report chronic cluster headache deep brain stimulation hypothalamus long-term outcome

来  源:   DOI:10.7759/cureus.47338   PDF(Pubmed)

Abstract:
Chronic cluster headache (CCH) is a debilitating primary headache that causes excruciating pain without remission. Various medical and surgical treatments have been implemented over the years, yet many provide only short-term relief. Deep brain stimulation (DBS) is an emerging treatment alternative that has been shown to dramatically reduce the intensity and frequency of headache attacks. However, reports of greater than 10-year outcomes after DBS for CCH are scant. Here, we report the durability of DBS in the posterior inferior hypothalamus after 10 years on a patient with CCH. Our patient experienced an 82% decrease in the frequency of headaches after DBS, which was maintained for over 10 years. The side effects observed included depression, irritability, anxiety, and dizziness, which were alleviated by changing programming settings. In the context of current literature, DBS shows promise for long-term relief of cluster headaches when other treatments fail.
摘要:
慢性丛集性头痛(CCH)是一种使人衰弱的原发性头痛,可引起剧烈的疼痛而无法缓解。多年来实施了各种医疗和手术治疗,然而,许多人只提供短期救济。深部脑刺激(DBS)是一种新兴的治疗方法,已被证明可以显着降低头痛发作的强度和频率。然而,CCHDBS后超过10年结果的报告很少。这里,我们报道了1例CCH患者10年后下丘脑后下丘脑DBS的持久性.我们的患者在DBS后头痛频率下降了82%,维持了10多年。观察到的副作用包括抑郁,烦躁,焦虑,头晕,通过更改编程设置来缓解。在当前文学的背景下,当其他治疗失败时,DBS有望长期缓解丛集性头痛。
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