Abstract:
Objective This study aims to assess the knowledge and attitudes toward clinical trial (CT) participation among the adult population in the Eastern Province of Saudi Arabia. Material and methods This cross-sectional study was conducted among the population of the Eastern Province of Saudi Arabia. A self-administered questionnaire was distributed among the general population using an online survey. Results A total of 334 participants completed the questionnaire. Participants\' ages ranged from 18 to 65 years, with a mean age of 31.2 ± 13.9 years, 56.6% of whom were males, 42.2% were employed, 29.6% were students, and 23.1% were unemployed. Surprisingly, only a small percentage of respondents (7.5%) were requested to participate in a randomized controlled trial (RCT), of which the majority did partake. Additionally, 25.4% of participants believe CTs are used to evaluate new drugs; others believe that CTs are used to understand diseases and human behavior. The data show that most participants believe that CTs improve patient care, welfare, and society. Also, participants were more likely to take part if they were aware of the study\'s purpose and findings and were given more time to consider their options. Conclusion Participants believed that the biggest obstacle was a lack of knowledge of CTs. It is crucial to educate patients more about CTs. Multimodal strategies such as improved patient-provider communication and online information for trial information sharing may be effective in boosting knowledge and CT recruitment.
摘要:
目的本研究旨在评估沙特阿拉伯东部省成年人对临床试验(CT)参与的知识和态度。材料和方法这项横断面研究是在沙特阿拉伯东部省的人口中进行的。使用在线调查在普通人群中分发了一份自我管理的问卷。结果共有334名参与者完成问卷。参与者的年龄从18岁到65岁不等,平均年龄为31.2±13.9岁,其中56.6%是男性,42.2%被雇用,29.6%是学生,23.1%的人失业。令人惊讶的是,只有一小部分受访者(7.5%)被要求参加随机对照试验(RCT),其中大多数人都参与了。此外,25.4%的参与者认为CT用于评估新药;其他人认为CT用于了解疾病和人类行为。数据显示,大多数参与者认为CT可以改善患者护理,福利,和社会。此外,如果参与者知道研究的目的和发现,并且有更多的时间考虑他们的选择,他们更有可能参加。结论参与者认为最大的障碍是缺乏CT知识。对患者进行更多关于CT的教育是至关重要的。多模式策略,例如改善患者与提供者的交流和用于试验信息共享的在线信息,可能会有效地提高知识和CT招募。