关键词: nontuberculous mycobacteria skin and soft tissue infections topical antibiotic treatment

Mesh : Humans Anti-Bacterial Agents / therapeutic use Nontuberculous Mycobacteria Soft Tissue Infections / drug therapy surgery Mycobacterium Infections, Nontuberculous / drug therapy surgery microbiology Skin

来  源:   DOI:10.1128/aac.00788-23   PDF(Pubmed)

Abstract:
Treatment of skin and soft tissue infections with nontuberculous mycobacteria sometimes fails despite repeated debridements and long-term systemic antibiotic therapy. These treatment-refractory infections can cause significant morbidity and pose a treatment challenge. Following surgery, we treated three patients with negative pressure wound therapy with the instillation and dwell time of topical antibiotics, in addition to systemic antibiotic treatment. Treatment was successful and well tolerated, except for some local irritation.
摘要:
尽管反复清创术和长期的全身性抗生素治疗,非结核分枝杆菌治疗皮肤和软组织感染有时会失败。这些治疗难治性感染可引起显著的发病率并构成治疗挑战。手术后,我们用局部抗生素滴注和停留时间的负压伤口疗法治疗了三名患者,除了全身抗生素治疗。治疗成功且耐受性良好,除了一些局部刺激。
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