PDF(Pubmed)
Abstract：
UNASSIGNED: A previous study demonstrated upper eyelid retraction synchronized with pupil dilation following a transition from photopic to scotopic conditions. The current study aimed to evaluate the role of Müller\'s muscle as the efferent arm of this suggested reflex arc.
UNASSIGNED: A video scan of both eyes of patients with unilateral Horner syndrome was performed using optical coherence tomography infra-red mode to document the transition between photopic and scotopic conditions. The affected side with sympathetic denervation was the study group, whereas the contralateral unaffected side of the same patients served as the control group. The pupil diameter, upper eyelid margin-to-reflex distance 1, lower eyelid margin-to-reflex distance 2, and vertical palpebral fissure height were measured. The control group was compared to the healthy subjects of a previous study to verify any compensatory changes to the side contralateral to denervation.
UNASSIGNED: Ten patients with unilateral Horner Syndrome were included in the study. Transitioning from photopic to scotopic conditions, the mean change in margin-to-reflex distance 1 in the study and control groups was 315 ± 276 µm (P < 0.05) and 723 ± 432 µm (P = 0.005), respectively. Margin-to-reflex distance 1 and palpebral fissure height were significantly higher in the control group both in photopic (P = 0.005 and P = 0.017, respectively) and scotopic conditions (P = 0.005 and P = 0.007, respectively). The change in margin-to-reflex distance 1 and palpebral fissure height following the transition from light to dark was significantly greater in the control group (P = 0.022).
UNASSIGNED: Reflexive eyelid retraction following a transition from photopic to scotopic conditions was significantly diminished in eyelids with sympathetic denervation compared with the unaffected contralateral side of the same patients. This study provides further evidence that the sympathetically innervated Müller\'s muscle serves as the efferent arm of this reflex.
UNASSIGNED: A video scan of both eyes of patients with unilateral Horner syndrome was performed using optical coherence tomography infra-red mode to document the transition between photopic and scotopic conditions. The affected side with sympathetic denervation was the study group, whereas the contralateral unaffected side of the same patients served as the control group. The pupil diameter, upper eyelid margin-to-reflex distance 1, lower eyelid margin-to-reflex distance 2, and vertical palpebral fissure height were measured. The control group was compared to the healthy subjects of a previous study to verify any compensatory changes to the side contralateral to denervation.
UNASSIGNED: Ten patients with unilateral Horner Syndrome were included in the study. Transitioning from photopic to scotopic conditions, the mean change in margin-to-reflex distance 1 in the study and control groups was 315 ± 276 µm (P < 0.05) and 723 ± 432 µm (P = 0.005), respectively. Margin-to-reflex distance 1 and palpebral fissure height were significantly higher in the control group both in photopic (P = 0.005 and P = 0.017, respectively) and scotopic conditions (P = 0.005 and P = 0.007, respectively). The change in margin-to-reflex distance 1 and palpebral fissure height following the transition from light to dark was significantly greater in the control group (P = 0.022).
UNASSIGNED: Reflexive eyelid retraction following a transition from photopic to scotopic conditions was significantly diminished in eyelids with sympathetic denervation compared with the unaffected contralateral side of the same patients. This study provides further evidence that the sympathetically innervated Müller\'s muscle serves as the efferent arm of this reflex.
摘要：
■先前的研究表明，从明视状态过渡到暗视状态后，上眼睑回缩与瞳孔扩张同步。当前的研究旨在评估穆勒肌肉作为该建议反射弧的传出臂的作用。
■使用光学相干断层扫描红外模式对单侧霍纳综合征患者的双眼进行视频扫描，以记录明视和暗视条件之间的过渡。受影响的一侧是交感神经支配的研究组，而相同患者的对侧未受影响的一侧作为对照组。瞳孔直径，测量上眼睑边缘至反射距离1，下眼睑边缘至反射距离2和垂直睑裂高度。将对照组与先前研究的健康受试者进行比较，以验证去神经对侧的代偿变化。
■10例单侧霍纳综合征患者纳入研究。从明视到暗视条件的转变，研究组和对照组的边缘反射距离1的平均变化为315±276µm（P<0.05）和723±432µm（P=0.005），分别。在明视条件（分别为P=0.005和P=0.017）和暗视条件（分别为P=0.005和P=0.007）下，对照组的边缘到反射距离1和睑裂高度均显着高于对照组。对照组从明暗过渡后，边缘到反射距离1和睑裂高度的变化明显更大（P=0.022）。
■与相同患者的未受影响的对侧相比，交感神经支配的眼睑从明视状态转变为暗视状态后的反射眼睑回缩显着减少。这项研究提供了进一步的证据，表明受交感神经支配的Müller肌肉是这种反射的传出臂。
■使用光学相干断层扫描红外模式对单侧霍纳综合征患者的双眼进行视频扫描，以记录明视和暗视条件之间的过渡。受影响的一侧是交感神经支配的研究组，而相同患者的对侧未受影响的一侧作为对照组。瞳孔直径，测量上眼睑边缘至反射距离1，下眼睑边缘至反射距离2和垂直睑裂高度。将对照组与先前研究的健康受试者进行比较，以验证去神经对侧的代偿变化。
■10例单侧霍纳综合征患者纳入研究。从明视到暗视条件的转变，研究组和对照组的边缘反射距离1的平均变化为315±276µm（P<0.05）和723±432µm（P=0.005），分别。在明视条件（分别为P=0.005和P=0.017）和暗视条件（分别为P=0.005和P=0.007）下，对照组的边缘到反射距离1和睑裂高度均显着高于对照组。对照组从明暗过渡后，边缘到反射距离1和睑裂高度的变化明显更大（P=0.022）。
■与相同患者的未受影响的对侧相比，交感神经支配的眼睑从明视状态转变为暗视状态后的反射眼睑回缩显着减少。这项研究提供了进一步的证据，表明受交感神经支配的Müller肌肉是这种反射的传出臂。
