Abstract：
BACKGROUND: Very few reports have evaluated the safety of laparoscopic liver resection in super-elderly patients. We assessed the short-term outcomes of laparoscopic liver resection in patients with hepatocellular carcinoma aged ≥80 years, using propensity score matching.
METHODS: We retrospectively analyzed the data of 287 patients (aged ≥80 years) who underwent liver resection for hepatocellular carcinoma at eight hospitals belonging to Hiroshima Surgical study group of Clinical Oncology, between January 2012 and December 2021. The perioperative outcomes were compared between laparoscopic and open liver resection, using propensity score matching.
RESULTS: Of the 287 patients, 83 and 204 were included in the laparoscopic and open liver resection groups, respectively. Propensity score matching was performed, and 52 patients were included in each group. The operation (p = .68) and pringle maneuver (p = .11) time were not different between the groups. There were no significant differences in the incidences of bile leakage or organ failure. The laparoscopic liver resection group had significantly less intraoperative bleeding and a lower incidence of cardiopulmonary complications (both p < .01).
CONCLUSIONS: Laparoscopic liver resection can be safely performed in elderly patients aged ≥80 years.
METHODS: We retrospectively analyzed the data of 287 patients (aged ≥80 years) who underwent liver resection for hepatocellular carcinoma at eight hospitals belonging to Hiroshima Surgical study group of Clinical Oncology, between January 2012 and December 2021. The perioperative outcomes were compared between laparoscopic and open liver resection, using propensity score matching.
RESULTS: Of the 287 patients, 83 and 204 were included in the laparoscopic and open liver resection groups, respectively. Propensity score matching was performed, and 52 patients were included in each group. The operation (p = .68) and pringle maneuver (p = .11) time were not different between the groups. There were no significant differences in the incidences of bile leakage or organ failure. The laparoscopic liver resection group had significantly less intraoperative bleeding and a lower incidence of cardiopulmonary complications (both p < .01).
CONCLUSIONS: Laparoscopic liver resection can be safely performed in elderly patients aged ≥80 years.
摘要：
背景：很少有报道评估超高龄患者腹腔镜肝切除术的安全性。我们评估了年龄≥80岁的肝细胞癌患者腹腔镜肝切除术的短期预后。使用倾向得分匹配。
方法：我们回顾性分析了在广岛临床肿瘤学外科研究组的八家医院接受肝细胞癌肝切除术的287例患者（年龄≥80岁）的数据，2012年1月至2021年12月。比较腹腔镜与开腹肝切除术的围手术期结局,使用倾向得分匹配。
结果：在287名患者中，腹腔镜和开腹肝切除组83例和204例，分别。进行倾向得分匹配，每组52例患者。两组之间的操作（p=.68）和操作（p=.11）时间没有差异。胆漏或器官衰竭的发生率没有显着差异。腹腔镜肝切除组术中出血明显少，心肺并发症发生率较低（均P<0.01）。
结论：腹腔镜肝切除术可安全适用于年龄≥80岁的老年患者。
方法：我们回顾性分析了在广岛临床肿瘤学外科研究组的八家医院接受肝细胞癌肝切除术的287例患者（年龄≥80岁）的数据，2012年1月至2021年12月。比较腹腔镜与开腹肝切除术的围手术期结局,使用倾向得分匹配。
结果：在287名患者中，腹腔镜和开腹肝切除组83例和204例，分别。进行倾向得分匹配，每组52例患者。两组之间的操作（p=.68）和操作（p=.11）时间没有差异。胆漏或器官衰竭的发生率没有显着差异。腹腔镜肝切除组术中出血明显少，心肺并发症发生率较低（均P<0.01）。
结论：腹腔镜肝切除术可安全适用于年龄≥80岁的老年患者。
