Abstract：
BACKGROUND: Previous studies demonstrated conflicting results regarding the determinants of gastric emptying for fluids. Our aim was to compare gastric emptying times of fluids with different caloric and nutrient content.
METHODS: Healthy adult volunteers underwent gastric ultrasound assessment for 4 h after consuming beverages with different caloric and nutrient content using a crossover design (oat drink with 3% fat [310 kcal], mango juice [310 kcal], oat drink with 0.5% fat [185 kcal], and blackcurrant juice [175 kcal]). Gastric emptying time, gastric content volume, and the area under the curve (AUC) of gastric content volume-time profiles were calculated.
RESULTS: Eight females and eight males completed the study protocol. The mean (sd) gastric emptying times were 89 (32) min for blackcurrant juice, 127 (54) min for oat drink with 0.5% fat, 135 (36) min for mango juice, and 152 (40) min for oat drink with 3% fat. Gastric emptying times were slower for oat drink with 3% fat (P=0.007) and mango juice (P=0.025) than for blackcurrant juice. At 1 h after ingestion, gastric content volume was greater for mango juice (P=0.021) and oat drink with 3% fat (P=0.003) than for blackcurrant juice. The AUC was greater for oat drink with 3% fat than mango juice (P=0.029), oat drink with 0.5% fat (P=0.004), and blackcurrant juice (P=0.002), and for mango juice than blackcurrant juice (P=0.019).
CONCLUSIONS: Caloric and nutrient content significantly affected gastric emptying times. A high-calorie fruit juice (mango) exhibited delayed emptying times compared with a low-calorie fruit juice (blackcurrant).
BACKGROUND: ISRCTN17147574.
METHODS: Healthy adult volunteers underwent gastric ultrasound assessment for 4 h after consuming beverages with different caloric and nutrient content using a crossover design (oat drink with 3% fat [310 kcal], mango juice [310 kcal], oat drink with 0.5% fat [185 kcal], and blackcurrant juice [175 kcal]). Gastric emptying time, gastric content volume, and the area under the curve (AUC) of gastric content volume-time profiles were calculated.
RESULTS: Eight females and eight males completed the study protocol. The mean (sd) gastric emptying times were 89 (32) min for blackcurrant juice, 127 (54) min for oat drink with 0.5% fat, 135 (36) min for mango juice, and 152 (40) min for oat drink with 3% fat. Gastric emptying times were slower for oat drink with 3% fat (P=0.007) and mango juice (P=0.025) than for blackcurrant juice. At 1 h after ingestion, gastric content volume was greater for mango juice (P=0.021) and oat drink with 3% fat (P=0.003) than for blackcurrant juice. The AUC was greater for oat drink with 3% fat than mango juice (P=0.029), oat drink with 0.5% fat (P=0.004), and blackcurrant juice (P=0.002), and for mango juice than blackcurrant juice (P=0.019).
CONCLUSIONS: Caloric and nutrient content significantly affected gastric emptying times. A high-calorie fruit juice (mango) exhibited delayed emptying times compared with a low-calorie fruit juice (blackcurrant).
BACKGROUND: ISRCTN17147574.
摘要：
背景：先前的研究表明，关于胃排空液体的决定因素的结果相互矛盾。我们的目的是比较不同热量和营养素含量的液体的胃排空时间。
方法：健康的成年志愿者在饮用不同热量和营养成分的饮料后4小时进行胃超声评估，采用交叉设计（含3％脂肪的燕麦饮料[310千卡]，芒果汁[310千卡]，含0.5%脂肪[185千卡]的燕麦饮料，和黑醋栗汁[175千卡])。胃排空时间,胃内容物体积，计算胃内容物体积-时间曲线下面积(AUC)。
结果：8名女性和8名男性完成了研究方案。黑醋栗汁的平均（SD）胃排空时间为89（32）分钟，含0.5%脂肪的燕麦饮料127(54)分钟，芒果汁135(36)分钟，含3%脂肪的燕麦饮料为152（40）分钟。含3％脂肪（P=0.007）和芒果汁（P=0.025）的燕麦饮料的胃排空时间比黑醋栗汁慢。在摄入后1小时，芒果汁（P=0.021）和含3％脂肪的燕麦饮料（P=0.003）的胃内容物体积大于黑醋栗汁。含3%脂肪的燕麦饮料的AUC高于芒果汁(P=0.029),含0.5%脂肪的燕麦饮料（P=0.004），和黑醋栗汁（P=0.002），且芒果汁优于黑醋栗汁(P=0.019)。
结论：热量和营养素含量显著影响胃排空时间。与低热量果汁（黑醋栗）相比，高热量果汁（芒果）的排空时间延迟。
背景：ISRCTN17147574。
方法：健康的成年志愿者在饮用不同热量和营养成分的饮料后4小时进行胃超声评估，采用交叉设计（含3％脂肪的燕麦饮料[310千卡]，芒果汁[310千卡]，含0.5%脂肪[185千卡]的燕麦饮料，和黑醋栗汁[175千卡])。胃排空时间,胃内容物体积，计算胃内容物体积-时间曲线下面积(AUC)。
结果：8名女性和8名男性完成了研究方案。黑醋栗汁的平均（SD）胃排空时间为89（32）分钟，含0.5%脂肪的燕麦饮料127(54)分钟，芒果汁135(36)分钟，含3%脂肪的燕麦饮料为152（40）分钟。含3％脂肪（P=0.007）和芒果汁（P=0.025）的燕麦饮料的胃排空时间比黑醋栗汁慢。在摄入后1小时，芒果汁（P=0.021）和含3％脂肪的燕麦饮料（P=0.003）的胃内容物体积大于黑醋栗汁。含3%脂肪的燕麦饮料的AUC高于芒果汁(P=0.029),含0.5%脂肪的燕麦饮料（P=0.004），和黑醋栗汁（P=0.002），且芒果汁优于黑醋栗汁(P=0.019)。
结论：热量和营养素含量显著影响胃排空时间。与低热量果汁（黑醋栗）相比，高热量果汁（芒果）的排空时间延迟。
背景：ISRCTN17147574。
