PDF(Pubmed)
Abstract：
Behavioral and psychological symptoms of dementia (BPSD) are present in most people with dementia (PwD), including Alzheimer\'s disease. There is consensus that non-pharmacological therapies represent the first line of treatment to address BPSD.
We explore the efficacy of the use of a rocking chair (Nordic Sensi® Chair, NSC) in the treatment of BPSD in nursing home residents with moderate and severe dementia.
We carried out a 16-week randomized, single-blind, controlled, clinical trial with PwD admitted to nursing homes. Participants were assigned to a treatment group (n = 40) that received three times a week one session per day of 20 minutes in the NSC and a control group (n = 37). The Neuropsychiatric Inventory-Nursing Home (NPI-NH) was used as primary efficacy outcome. Occupational distress for the staff was evaluated using the NPI-NH Occupational Disruptiveness subscale (NPI-NH-OD). Statistical analyses were conducted by means of a Mixed Effects Model Analysis.
Treatment with the NSC was associated with a beneficial effect in most of BPSD, as reflected by differences between the treatment and control group on the NPI-NH total score (mean change score -18.87±5.56 versus -1.74±0.67, p = 0.004), agitation (mean change score -2.32±2.02 versus -0.78±1.44, p = 0.003) and irritability (mean change score -3.35±2.93 versus -1.42±1.31, p = 0.004). The NPI-NH-OD total score also improved the most in the treatment group (mean change score -9.67±7.67 versus -7.66±6.08, p = 0.003).
The reduction in overall BPSD along with decreased caregiver occupational disruptiveness represent encouraging findings, adding to the potential of nonpharmacological interventions for nursing home residents living with dementia.
We explore the efficacy of the use of a rocking chair (Nordic Sensi® Chair, NSC) in the treatment of BPSD in nursing home residents with moderate and severe dementia.
We carried out a 16-week randomized, single-blind, controlled, clinical trial with PwD admitted to nursing homes. Participants were assigned to a treatment group (n = 40) that received three times a week one session per day of 20 minutes in the NSC and a control group (n = 37). The Neuropsychiatric Inventory-Nursing Home (NPI-NH) was used as primary efficacy outcome. Occupational distress for the staff was evaluated using the NPI-NH Occupational Disruptiveness subscale (NPI-NH-OD). Statistical analyses were conducted by means of a Mixed Effects Model Analysis.
Treatment with the NSC was associated with a beneficial effect in most of BPSD, as reflected by differences between the treatment and control group on the NPI-NH total score (mean change score -18.87±5.56 versus -1.74±0.67, p = 0.004), agitation (mean change score -2.32±2.02 versus -0.78±1.44, p = 0.003) and irritability (mean change score -3.35±2.93 versus -1.42±1.31, p = 0.004). The NPI-NH-OD total score also improved the most in the treatment group (mean change score -9.67±7.67 versus -7.66±6.08, p = 0.003).
The reduction in overall BPSD along with decreased caregiver occupational disruptiveness represent encouraging findings, adding to the potential of nonpharmacological interventions for nursing home residents living with dementia.
摘要：
背景：痴呆（BPSD）的行为和心理症状存在于大多数痴呆（PwD）患者中，包括老年痴呆症.人们一致认为非药物疗法代表了解决BPSD的一线治疗。
目的：我们探索使用摇椅（NordicSensi®Chair，NSC）在患有中度和重度痴呆的疗养院居民中治疗BPSD。
方法：我们进行了为期16周的随机，单盲,控制,纳入疗养院的PwD临床试验。参与者被分配到治疗组（n=40）和对照组（n=37），该治疗组每周接受3次，每天20分钟的疗程。神经精神清单-疗养院（NPI-NH）被用作主要疗效结果。使用NPI-NH职业破坏力子量表（NPI-NH-OD）评估了员工的职业困扰。通过混合效应模型分析进行统计分析。
结果：在大多数BPSD中，使用NSC治疗与有益效果相关，如治疗组和对照组在NPI-NH总分上的差异（平均变化评分-18.87±5.56对-1.74±0.67，p=0.004），躁动（平均变化评分-2.32±2.02对-0.78±1.44，p=0.003）和易怒（平均变化评分-3.35±2.93对-1.42±1.31，p=0.004）。NPI-NH-OD总评分在治疗组中也改善最大(平均变化评分-9.67±7.67对-7.66±6.08,p=0.003)。
结论：总体BPSD的减少以及护理人员职业干扰的减少代表了令人鼓舞的发现，为患有痴呆症的疗养院居民增加非药物干预的潜力。
目的：我们探索使用摇椅（NordicSensi®Chair，NSC）在患有中度和重度痴呆的疗养院居民中治疗BPSD。
方法：我们进行了为期16周的随机，单盲,控制,纳入疗养院的PwD临床试验。参与者被分配到治疗组（n=40）和对照组（n=37），该治疗组每周接受3次，每天20分钟的疗程。神经精神清单-疗养院（NPI-NH）被用作主要疗效结果。使用NPI-NH职业破坏力子量表（NPI-NH-OD）评估了员工的职业困扰。通过混合效应模型分析进行统计分析。
结果：在大多数BPSD中，使用NSC治疗与有益效果相关，如治疗组和对照组在NPI-NH总分上的差异（平均变化评分-18.87±5.56对-1.74±0.67，p=0.004），躁动（平均变化评分-2.32±2.02对-0.78±1.44，p=0.003）和易怒（平均变化评分-3.35±2.93对-1.42±1.31，p=0.004）。NPI-NH-OD总评分在治疗组中也改善最大(平均变化评分-9.67±7.67对-7.66±6.08,p=0.003)。
结论：总体BPSD的减少以及护理人员职业干扰的减少代表了令人鼓舞的发现，为患有痴呆症的疗养院居民增加非药物干预的潜力。
