Abstract:
Turnera is a genus of plants whose biological activity has been widely studied. The importance of this genus, particularly Turnera diffusa, as a source of treatment for various conditions is evidenced by the large number of new studies that have evaluated its biological activity. Accordingly, the objective of this review was to compile the information published in the last ten years concerning the biological activities reported for Turnera spp. The present work includes 92 publications that evaluate 29 bioactivities and toxicological and genotoxic information on five species of this genus. Among the pharmacological effects reported, the antioxidant, hepatoprotective, neuroprotective, hypoglycemic, and aphrodisiac activities seem more promising. Phytochemicals and standardized plant extracts could offer alternative therapeutic remedies for various diseases. Although several flavonoids, cyanogenic glycosides, monoterpenoids, triterpenoids, and fatty acids have been isolated for Turnera plants, future research should focus on the identification of the main active principles responsible for these pharmacological activities, as well as to perform clinical trials to support the laboratory results.
摘要:
Turnera是一种植物,其生物活性已被广泛研究。这个属的重要性,尤其是吐槽,作为各种疾病的治疗来源,大量评估其生物活性的新研究证明了这一点。因此,本综述的目的是汇编过去10年发表的有关Turneraspp生物活性的信息.目前的工作包括92种出版物,这些出版物评估了该属5种物种的29种生物活性以及毒理学和遗传毒性信息。在报道的药理作用中,抗氧化剂,保肝,神经保护,低血糖,壮阳活动似乎更有希望。植物化学物质和标准化的植物提取物可以为各种疾病提供替代的治疗方法。虽然几种类黄酮,生氰苷,单萜,三萜类,和脂肪酸已经被分离用于Turnera植物,未来的研究应该集中在确定负责这些药理活性的主要活性成分,以及进行临床试验以支持实验室结果。