Abstract：
We set out to estimate the international incidence of rhegmatogenous retinal detachment (RRD) and to evaluate its temporal trend over time. There is a lack of robust estimates on the worldwide incidence and trend for RRD, a major cause of acute vision loss. We conducted a systematic review of RRD incidence. The electronic databases PubMed, Scopus, and Thomson Reuters\' Web of Science were searched from inception through 2nd June 2022. Random-effects meta-analysis model with logit transformation was performed to obtain pooled annual incidence estimates of RRD. Pooled analysis was performed to evaluate the temporal trend of RRD incidence of the 20,958 records identified from the database searches; 33 studies from 21 countries were included for analysis (274,836 cases of RRD in 273,977 persons). Three of the 6 global regions as defined by WHO had studies that met the inclusion and exclusion criteria of the study. The annual international incidence of RRD was estimated to be 12.17 (95% confidence interval [CI] 10.51-14.09) per 100,000 population; with an increasing temporal trend of RRD at 5.4 per 100,000 per decade (p 0.001) from 1997 to 2019. Amongst world regions, the RRD incidence was highest in Europe (14.52 [95% CI 11.79 - 17.88] per 100,000 population), followed by Western Pacific (10.55 [95% CI 8.71-12.75] per 100,000 population) and Regions of Americas (8.95 [95% CI 6.73-11.92] per 100,000 population). About one in 10,000 persons develop RRD each year. There is evidence of increasing trend for RRD incidence over time, with possibly doubling of the current incidence rate within the next 2 decades.
摘要：
我们着手估计孔源性视网膜脱离（RRD）的国际发病率，并评估其随时间的时间趋势。对RRD的全球发病率和趋势缺乏可靠的估计，急性视力丧失的主要原因.我们对RRD发生率进行了系统评价。电子数据库PubMed，Scopus,和汤森路透的WebofScience从成立到2022年6月2日进行了搜索。使用Logit转换的随机效应荟萃分析模型来获得RRD的汇总年发病率估计值。进行汇总分析以评估RRD发生率的时间趋势。在从数据库搜索中确定的20958条记录中，来自21个国家的33项研究被纳入分析(273,977人中有274,836例RRD)。世卫组织定义的6个全球区域中有3个区域的研究符合研究的纳入和排除标准。RRD的年度国际发病率估计为每100,000人口12.17（95％置信区间[CI]10.51-14.09）；从1997年到2019年，RRD的时间趋势为每十年5.4/100,000（p<0.001）。在世界各地区，RRD发病率在欧洲最高(每100,000人口14.52[95%CI11.79-17.88])，其次是西太平洋(每100,000人口10.55[95%CI8.71-12.75])和美洲区域(每100,000人口8.95[95%CI6.73-11.92])。每年约有万分之一的人发展RRD。有证据表明，随着时间的推移，RRD发病率有增加的趋势，在未来20年内，目前的发病率可能会翻一番。
