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Abstract：
This scoping review aims to identify and synthesise existing statistical methods used to assess the progress of HIV treatment programmes in terms of the HIV cascade and continuum of care among people living with HIV (PLHIV).
Systematic scoping review.
Published articles were retrieved from PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL) Complete and Excerpta Medica dataBASE (EMBASE) databases between April and July 2022. We also strategically search using the Google Scholar search engine and reference lists of published articles.
This scoping review included original English articles that estimated and described the HIV cascade and continuum of care progress in PLHIV. The review considered quantitative articles that evaluated either HIV care cascade progress in terms of the Joint United Nations Programme on HIV and AIDS targets or the dynamics of engagement in HIV care.
The first author and the librarian developed database search queries and screened the retrieved titles and abstracts. Two independent reviewers and the first author extracted data using a standardised data extraction tool. The data analysis was descriptive and the findings are presented in tables and visuals.
This review included 300 articles. Cross-sectional study design methods were the most commonly used to assess the HIV care cascade (n=279, 93%). In cross-sectional and longitudinal studies, the majority used proportions to describe individuals at each cascade stage (276/279 (99%) and 20/21 (95%), respectively). In longitudinal studies, the time spent in cascade stages, transition probabilities and cumulative incidence functions was estimated. The logistic regression model was common in both cross-sectional (101/279, 36%) and longitudinal studies (7/21, 33%). Of the 21 articles that used a longitudinal design, six articles used multistate models, which included non-parametric, parametric, continuous-time, time-homogeneous and discrete-time multistate Markov models.
Most literature on the HIV cascade and continuum of care arises from cross-sectional studies. The use of longitudinal study design methods in the HIV cascade is growing because such methods can provide additional information about transition dynamics along the cascade. Therefore, a methodological guide for applying different types of longitudinal design methods to the HIV continuum of care assessments is warranted.
Systematic scoping review.
Published articles were retrieved from PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL) Complete and Excerpta Medica dataBASE (EMBASE) databases between April and July 2022. We also strategically search using the Google Scholar search engine and reference lists of published articles.
This scoping review included original English articles that estimated and described the HIV cascade and continuum of care progress in PLHIV. The review considered quantitative articles that evaluated either HIV care cascade progress in terms of the Joint United Nations Programme on HIV and AIDS targets or the dynamics of engagement in HIV care.
The first author and the librarian developed database search queries and screened the retrieved titles and abstracts. Two independent reviewers and the first author extracted data using a standardised data extraction tool. The data analysis was descriptive and the findings are presented in tables and visuals.
This review included 300 articles. Cross-sectional study design methods were the most commonly used to assess the HIV care cascade (n=279, 93%). In cross-sectional and longitudinal studies, the majority used proportions to describe individuals at each cascade stage (276/279 (99%) and 20/21 (95%), respectively). In longitudinal studies, the time spent in cascade stages, transition probabilities and cumulative incidence functions was estimated. The logistic regression model was common in both cross-sectional (101/279, 36%) and longitudinal studies (7/21, 33%). Of the 21 articles that used a longitudinal design, six articles used multistate models, which included non-parametric, parametric, continuous-time, time-homogeneous and discrete-time multistate Markov models.
Most literature on the HIV cascade and continuum of care arises from cross-sectional studies. The use of longitudinal study design methods in the HIV cascade is growing because such methods can provide additional information about transition dynamics along the cascade. Therefore, a methodological guide for applying different types of longitudinal design methods to the HIV continuum of care assessments is warranted.
摘要：
目的：本范围审查旨在确定和综合现有的统计方法，用于评估HIV感染者（PLHIV）中HIV级联和持续护理方面的HIV治疗计划进展。
方法：系统范围审查。
方法：已发布的文章是从PubMed检索的，2022年4月至7月之间的护理和相关健康文献累积指数（CINAHL）完整和摘录医学数据库（EMBASE）数据库。我们还使用GoogleScholar搜索引擎和已发表文章的参考列表进行战略性搜索。
方法：本范围审查包括原版英文文章，这些文章估计和描述了PLHIV中的HIV级联和护理进展的连续性。审查考虑了定量文章，这些文章从联合国艾滋病毒和艾滋病联合规划署的目标或参与艾滋病毒护理的动态方面评估了艾滋病毒护理级联进展。
方法：第一作者和图书馆员开发了数据库搜索查询，并筛选了检索到的标题和摘要。两名独立的审阅者和第一作者使用标准化的数据提取工具提取数据。数据分析是描述性的，结果以表格和视觉效果呈现。
结果：这篇综述包括300篇文章。横断面研究设计方法最常用于评估HIV护理级联（n=279，93%）。在横截面和纵向研究中，大多数使用比例来描述每个级联阶段的个体(276/279(99%)和20/21(95%)，分别)。在纵向研究中，在级联阶段花费的时间，估计了转移概率和累积发生率函数。Logistic回归模型在横断面研究（101/279，36%）和纵向研究（7/21，33%）中都很常见。在使用纵向设计的21篇文章中，六篇文章使用了多态模型，其中包括非参数，参数化,连续时间,时间齐次和离散时间多状态马尔可夫模型。
结论：大多数关于HIV级联和持续护理的文献来自横断面研究。在HIV级联中使用纵向研究设计方法正在增长，因为这种方法可以提供有关级联过渡动力学的其他信息。因此,有必要制定将不同类型的纵向设计方法应用于HIV连续护理评估的方法学指南.
方法：系统范围审查。
方法：已发布的文章是从PubMed检索的，2022年4月至7月之间的护理和相关健康文献累积指数（CINAHL）完整和摘录医学数据库（EMBASE）数据库。我们还使用GoogleScholar搜索引擎和已发表文章的参考列表进行战略性搜索。
方法：本范围审查包括原版英文文章，这些文章估计和描述了PLHIV中的HIV级联和护理进展的连续性。审查考虑了定量文章，这些文章从联合国艾滋病毒和艾滋病联合规划署的目标或参与艾滋病毒护理的动态方面评估了艾滋病毒护理级联进展。
方法：第一作者和图书馆员开发了数据库搜索查询，并筛选了检索到的标题和摘要。两名独立的审阅者和第一作者使用标准化的数据提取工具提取数据。数据分析是描述性的，结果以表格和视觉效果呈现。
结果：这篇综述包括300篇文章。横断面研究设计方法最常用于评估HIV护理级联（n=279，93%）。在横截面和纵向研究中，大多数使用比例来描述每个级联阶段的个体(276/279(99%)和20/21(95%)，分别)。在纵向研究中，在级联阶段花费的时间，估计了转移概率和累积发生率函数。Logistic回归模型在横断面研究（101/279，36%）和纵向研究（7/21，33%）中都很常见。在使用纵向设计的21篇文章中，六篇文章使用了多态模型，其中包括非参数，参数化,连续时间,时间齐次和离散时间多状态马尔可夫模型。
结论：大多数关于HIV级联和持续护理的文献来自横断面研究。在HIV级联中使用纵向研究设计方法正在增长，因为这种方法可以提供有关级联过渡动力学的其他信息。因此,有必要制定将不同类型的纵向设计方法应用于HIV连续护理评估的方法学指南.
