PDF(Pubmed)
Abstract：
OBJECTIVE: People who inject drugs are at risk of acute infections, such as skin and soft tissue infections, infective endocarditis, bone and joint infections and bloodstream infections. There has been an increase in these infections in people who inject drugs internationally over the past 10 years. However, the local data regarding acute infections in Australia has not been well described.
METHODS: We review the epidemiology of acute infections and associated morbidity and mortality amongst people who inject drugs in Australia. We summarise risk factors for these infections, including the concurrent social and psychological determinants of health.
RESULTS: The proportion of people who report having injected drugs in the prior 12 months in Australia has decreased over the past 18 years. However, there has been an increase in the burden of acute infections in this population. This increase is driven largely by skin and soft tissue infections. People who inject drugs often have multiple conflicting priorities that can delay engagement in care.
CONCLUSIONS: Acute infections in people who inject drugs are associated with significant morbidity and mortality. Acute infections contribute to significant bed days, surgical requirements and health-care costs in Australia. The increase in these infections is likely due to a complex interplay of microbiological, individual, social and environmental factors.
CONCLUSIONS: Acute infections in people who inject drugs in Australia represent a significant burden to both patients and health-care systems. Flexible health-care models, such as low-threshold wound clinics, would help directly target, and address early interventions, for these infections.
METHODS: We review the epidemiology of acute infections and associated morbidity and mortality amongst people who inject drugs in Australia. We summarise risk factors for these infections, including the concurrent social and psychological determinants of health.
RESULTS: The proportion of people who report having injected drugs in the prior 12 months in Australia has decreased over the past 18 years. However, there has been an increase in the burden of acute infections in this population. This increase is driven largely by skin and soft tissue infections. People who inject drugs often have multiple conflicting priorities that can delay engagement in care.
CONCLUSIONS: Acute infections in people who inject drugs are associated with significant morbidity and mortality. Acute infections contribute to significant bed days, surgical requirements and health-care costs in Australia. The increase in these infections is likely due to a complex interplay of microbiological, individual, social and environmental factors.
CONCLUSIONS: Acute infections in people who inject drugs in Australia represent a significant burden to both patients and health-care systems. Flexible health-care models, such as low-threshold wound clinics, would help directly target, and address early interventions, for these infections.
摘要：
目标：注射药物的人有急性感染的风险，如皮肤和软组织感染，感染性心内膜炎,骨和关节感染和血流感染。在过去10年中，在国际上注射毒品的人中这些感染有所增加。然而,关于澳大利亚急性感染的当地数据尚未得到很好的描述.
方法：我们回顾了澳大利亚注射毒品人群中急性感染的流行病学及相关发病率和死亡率。我们总结了这些感染的危险因素，包括同时影响健康的社会和心理决定因素。
结果：在过去的18年中，澳大利亚报告在过去12个月内注射过药物的比例有所下降。然而,该人群的急性感染负担有所增加。这种增加主要由皮肤和软组织感染驱动。注射毒品的人通常有多个相互冲突的优先事项，这可能会延迟参与护理。
结论：注射药物者的急性感染与显著的发病率和死亡率相关。急性感染导致大量的卧床天数，澳大利亚的手术要求和医疗费用。这些感染的增加可能是由于微生物的复杂相互作用，个人,社会和环境因素。
结论：在澳大利亚注射药物者的急性感染对患者和卫生保健系统都是一个巨大的负担。灵活的医疗保健模式，例如低阈值伤口诊所，会有助于直接瞄准，并解决早期干预问题，这些感染。
方法：我们回顾了澳大利亚注射毒品人群中急性感染的流行病学及相关发病率和死亡率。我们总结了这些感染的危险因素，包括同时影响健康的社会和心理决定因素。
结果：在过去的18年中，澳大利亚报告在过去12个月内注射过药物的比例有所下降。然而,该人群的急性感染负担有所增加。这种增加主要由皮肤和软组织感染驱动。注射毒品的人通常有多个相互冲突的优先事项，这可能会延迟参与护理。
结论：注射药物者的急性感染与显著的发病率和死亡率相关。急性感染导致大量的卧床天数，澳大利亚的手术要求和医疗费用。这些感染的增加可能是由于微生物的复杂相互作用，个人,社会和环境因素。
结论：在澳大利亚注射药物者的急性感染对患者和卫生保健系统都是一个巨大的负担。灵活的医疗保健模式，例如低阈值伤口诊所，会有助于直接瞄准，并解决早期干预问题，这些感染。
