Abstract：
Cerebrospinal fluid (CSF) eosinophilia is associated with a narrow differential, primarily including parasitic and fungal infections, neoplasm, and chemical meningitis. It has rarely been reported in neuroinflammatory conditions including as a finding of CSF cytology in two autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy cases. Here we describe a case of autoimmune GFAP astrocytopathy with classic clinical and radiographic features as well as presence of eosinophils in the CSF. This case highlights a potential association of eosinophils in the CSF with autoimmune GFAP astrocytopathy, which may suggest its inclusion in the differential diagnosis of eosinophilic meningitis, encephalitis, or myelitis.
摘要：
脑脊液（CSF）嗜酸性粒细胞增多与狭窄的差异有关，主要包括寄生虫和真菌感染，肿瘤，和化学性脑膜炎.在神经炎症性疾病中很少有报道，包括在两个自身免疫性神经胶质纤维酸性蛋白（GFAP）星形细胞病病例中发现CSF细胞学。在这里，我们描述了一例自身免疫性GFAP星形细胞病，具有经典的临床和影像学特征以及CSF中嗜酸性粒细胞的存在。该病例强调了CSF中嗜酸性粒细胞与自身免疫性GFAP星形细胞病的潜在关联，这可能表明它包含在嗜酸性粒细胞性脑膜炎的鉴别诊断中，脑炎,或者脊髓炎.
