%0 Case Reports
%T case of autoimmune GFAP astrocytopathy with eosinophils in the cerebrospinal fluid.
%A Lowe MC
%A Money KM
%A Matthews E
%A Pastula DM
%A Piquet AL
%J J Neuroimmunol
%V 385
%N 0
%D 2023 12 15
%M 37992587
%F 3.221
%R 10.1016/j.jneuroim.2023.578249
%X Cerebrospinal fluid (CSF) eosinophilia is associated with a narrow differential, primarily including parasitic and fungal infections, neoplasm, and chemical meningitis. It has rarely been reported in neuroinflammatory conditions including as a finding of CSF cytology in two autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy cases. Here we describe a case of autoimmune GFAP astrocytopathy with classic clinical and radiographic features as well as presence of eosinophils in the CSF. This case highlights a potential association of eosinophils in the CSF with autoimmune GFAP astrocytopathy, which may suggest its inclusion in the differential diagnosis of eosinophilic meningitis, encephalitis, or myelitis.