METHODS: The patient chief complaints were right-side facial numbness and right-eyelid incomplete closure, followed by slurred speech and dysphagia, and the symptoms gradually progressed. The patient serum was positive for anti-AchR and anti-Titin antibodies.
METHODS: The patient was diagnosed FOSMN with MG.
METHODS: The patient symptoms were relieved after pyridostigmine bromide and prednisolone treatment.
RESULTS: Symptoms have improved.
CONCLUSIONS: Facial-onset sensory and motor neuronopathy and MG have disparate clinical features. Therefore, we reported a rare case in which the 2 conditions concurrently existed. Immune dysfunction might be the pathogenesis of this association, while there is no definite evidence to support it, further studies are needed.
方法:患者主诉是右侧面部麻木和右眼睑不完全闭合,其次是言语不清和吞咽困难,症状逐渐进展。患者血清抗AchR和抗Titin抗体呈阳性。
方法:患者诊断为FOSMN合并MG。
方法:患者经溴吡斯的明和泼尼松龙治疗后症状缓解。
结果:症状有所改善。
结论:面部发作的感觉和运动神经元病和MG具有不同的临床特征。因此,我们报道了一个罕见的病例,其中两种情况同时存在。免疫功能紊乱可能是这种关联的发病机制,虽然没有确切的证据支持,需要进一步的研究。