A total of 142 female patients, 71 cases and 71 controls, were analyzed in the study. Ages were matched in case and control groups and the mean age was 36.6 ± 8.2 (18 to 50) years. MCI consisting of C1 (Normal Mandibular Cortex), C2 (Moderately Resorbed Mandibular Cortex) and, C3 (Severely Resorbed Cortex) scores was determined for case and control groups. Fractal analysis was performed using ImageJ on selected regions of interest from the gonial and interdental regions. The box-count method was used to calculate FD values. Wilcoxon signed-rank test, Mann-Whitney U test, and Spearman correlation analysis were applied to compare the measurements. Statistical significance of differences was established at P < 0.05 level.
FD values did not show statistically significant differences between case and control groups (p > 0.05). The mean FD in the right gonial region was 1.38 ± 0.07 in the case group and 1.38 ± 0.08 in the control group (p = 0.715). The mean FD in the right interdental region was 1.37 ± 0.06 in the cases and 1.36 ± 0.06 in the control group (p = 0.373). The mean FD in the left gonial region was 1.39 ± 0.07 in the cases and 1.39 ± 0.07 in the control group (p = 0.865). The mean FD in the left interdental region is 1.37 ± 0.06 in the cases and 1.38 ± 0.05 in the control group (p = 0.369). The most common MCI score was C1, with 62% in the cases and 83.1% in the control group. MCI scores showed a statistically significant difference between cases and controls (p = 0.016, p < 0.05). While the C2 score was higher in the cases, the C1 score was higher in the controls.
LT4 use was not associated with the FD of mandibular trabecular bone, but was associated with MCI values of cortical bone. Further studies on larger samples with different imaging modalities and image processing methods are needed.
方法:共142例女性患者,71例病例和71例对照,在研究中进行了分析。病例组和对照组的年龄相匹配,平均年龄为36.6±8.2(18至50)岁。MCI由C1(正常下颌皮质)组成,C2(中度再吸收下颌皮质)和,确定病例组和对照组的C3(严重吸收皮质)评分。使用ImageJ对来自牙侧和齿间区域的所选择的感兴趣区域进行分形分析。盒计数方法用于计算FD值。Wilcoxon符号秩检验,Mann-WhitneyU测试,和Spearman相关分析用于比较测量值。在P<0.05水平建立统计学差异。
结果:FD值在病例组和对照组之间没有统计学上的显着差异(p>0.05)。病例组右侧前骨区域的平均FD为1.38±0.07,对照组为1.38±0.08(p=0.715)。病例右侧齿间区的平均FD为1.37±0.06,对照组为1.36±0.06(p=0.373)。病例组左侧房区平均FD为1.39±0.07,对照组为1.39±0.07(p=0.865)。病例组左侧齿间区的平均FD为1.37±0.06,对照组为1.38±0.05(p=0.369)。最常见的MCI评分为C1,病例为62%,对照组为83.1%。MCI评分在病例和对照组之间显示出统计学上的显着差异(p=0.016,p<0.05)。虽然C2评分较高的病例,对照组的C1评分较高.
结论:LT4的使用与下颌小梁骨的FD无关,但与皮质骨的MCI值相关。需要对具有不同成像模式和图像处理方法的较大样本进行进一步研究。