关键词: Epidemiology Senegal Stone composition Urolithiasis

Mesh : Male Young Adult Humans Adult Middle Aged Female Retrospective Studies Lithiasis Uric Acid Urolithiasis / epidemiology Urinary Calculi / chemistry Urinary Tract

来  源:   DOI:10.1007/s00240-023-01498-4

Abstract:
Urolithiasis is a major public health issue due to its increasing prevalence. The objective of this study was to describe the spectrophotometric profile of upper urinary tract stones (UTS) in Senegal. We conducted a multicenter retrospective study of all patients treated for upper UTS whose chemical composition was analyzed from January 2014 to January 2020 in eight regions of Senegal. Socio-demographic, clinical, paraclinical, and prognosis data were collected and analyzed. Three hundred and thirty-four patients were included in this study with a mean age of 46.3 ± 18.4 years and a sex ratio of 1.38. About one-third of patients (31.1%) had a body mass index > 25 kg/m2 and 74.2% presented with lumbar pain was the main clinical symptom. Calcium oxalate and calcium phosphate stones were the predominant types found, respectively, in 37.7% and 24.5% of patients. Uric acid was the main stone constituent in 18.6% of patients and struvites represented 14.7% of cases. Stones were located in the renal calyces and pelvis in 71.2% of cases. Surgical lithotomy was performed in 62.7% of patients for UTS extraction. Upper UTS are frequent condition in Senegalese with predominance of males and young adults. Calcium and uric acid stones are the main types. Preventive dietary and lifestyle measures are needed to reduce their burden.
摘要:
由于尿石症的患病率越来越高,因此尿石症是一个主要的公共卫生问题。这项研究的目的是描述塞内加尔上尿路结石(UTS)的分光光度分布。我们对2014年1月至2020年1月在塞内加尔8个地区接受UTS治疗的所有患者进行了多中心回顾性研究,分析了这些患者的化学成分。社会人口学,临床,临床旁,收集并分析预后资料。这项研究包括303名患者,平均年龄为46.3±18.4岁,性别比为1.38。约三分之一(31.1%)的患者体重指数>25kg/m2,74.2%的患者以腰痛为主要临床症状。草酸钙和磷酸钙结石是发现的主要类型,分别,37.7%和24.5%的患者。在18.6%的患者中,尿酸是主要的结石成分,而Strovites占14.7%。在71.2%的病例中,结石位于肾盏和骨盆中。62.7%的患者进行了手术取石术以进行UTS拔除。在塞内加尔,UTS上流社会是常见的疾病,主要是男性和年轻人。钙和尿酸结石是主要类型。需要采取预防性饮食和生活方式措施来减轻他们的负担。
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