Abstract：
Individuals with pre-clinical mobility limitation (PCML) are at a high risk of future functional loss and progression to disability. The purpose of this scoping review was to provide a comprehensive understanding of PCML intervention studies in middle-aged and older adults. We present the interventions that have been tested or planned, describe how they have been conducted and reported, identify the knowledge gaps in current literature, and make recommendations about future research directions. An initial search of 2,291 articles resulted in 14 articles that met criteria for inclusion. Findings reveal that: (1) there is limited published work on PCML interventions, especially in middle-aged populations; and (2) the complexity and variety of PCML measures make it difficult to compare findings across PCML studies. Despite the diversity of measures, this review provides preliminary evidence that rehabilitation interventions on PCML help to delay or prevent disability progression.
摘要：
具有临床前活动受限(PCML)的个体处于未来功能丧失和进展为残疾的高风险中。本研究的目的是全面了解中老年人的PCML干预研究。我们介绍已经测试或计划的干预措施，描述它们是如何进行和报告的，找出当前文献中的知识差距，并对未来的研究方向提出建议。最初检索了2291篇文章，结果有14篇文章符合列入标准。研究结果表明：(1)关于PCML干预措施的已发表工作有限，尤其是在中年人群中;(2)PCML措施的复杂性和多样性使得难以比较PCML研究的结果。尽管措施多种多样，本综述提供了对PCML的康复干预有助于延缓或预防残疾进展的初步证据.
