Abstract：
Pseudomyxoma peritonei (PMP) of pancreatic origin arising from an intraductal papillary mucinous neoplasm (IPMN) is rare. Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) has been established as the optimal treatment for PMP. However, the benefits and safety of CRS with HIPEC for treating PMP of pancreatic origin remain unclear. Herein, we describe a case of PMP of pancreatic origin that was treated with CRS and HIPEC without postoperative complications. A 75-year-old woman was referred to our department. Computed tomography (CT) revealed a multilocular cystic tumor in the pancreatic tail, notable mucinous ascites in the abdominal cavity, and scalloping of the liver and spleen. CT did not reveal the appendix, and the ovaries were normal in size. The patient was diagnosed with PMP of pancreatic origin, and CRS and HIPEC were performed. Intraoperatively, the pancreatic tumor was perforated, and there was a large amount of mucinous ascites. We performed distal pancreatectomy in addition to CRS and HIPEC, with no intraoperative complications. The postoperative course was uneventful, and the patient survived after 6 months without recurrence. CRS with HIPEC may be a feasible treatment option for PMP of pancreatic origin.
摘要：
由导管内乳头状粘液性肿瘤（IPMN）引起的胰腺起源的腹膜假粘液瘤（PMP）很少见。细胞减灭术（CRS）加腹腔热化疗（HIPEC）已被确定为PMP的最佳治疗方法。然而,CRS联合HIPEC治疗胰腺源性PMP的益处和安全性尚不清楚.在这里，我们描述了1例胰腺来源的PMP,采用CRS和HIPEC治疗,无术后并发症.一名75岁的妇女被转介到我们部门。计算机断层扫描（CT）显示胰腺尾部有多房性囊性肿瘤，腹腔有明显的黏液性腹水，肝脏和脾脏的扇贝。CT没有发现阑尾,卵巢大小正常.患者被诊断为胰腺来源的PMP，进行CRS和HIPEC。术中,胰腺肿瘤穿孔,还有大量的黏液性腹水.除了CRS和HIPEC外，我们还进行了远端胰腺切除术，术中无并发症。术后进展顺利，患者存活6个月后无复发。CRS合并HIPEC可能是胰腺来源PMP的可行治疗选择。
