Abstract：
Overweight and obesity are a public health problem and in 1997 obesity was recognized as a global epidemic by the World Health Organization (WHO). Overweight and obesity affect almost 60% of adults and one in three children in Europe according to the most recent WHO report. Objectively, gastroesophageal reflux disease (GERD) is defined as the presence of characteristic esophageal mucosal damage assessed by endoscopy and/or the demonstra-tion of pathological acid exposure by reflux monitoring studies. The prevalence of GERD is increased in obese patients In overweight and obese patients, the clinical symptoms of GERD are especially present in the supine position and this correlates with more frequent episodes of nocturnal reflux in the 24-h pH monitoring, there is also an increase in the number of refluxes with content acid. In the population with symptoms, digestive endoscopy detects data of erosive esophagitis in 50% of patients, while 24-h pH-impedanciometry diagnoses 92% of patients with non-erosive reflux disease (NERD) The presence of persistent GERD in the mucosa affects esophageal motility and patients may develop ineffective esophageal motility-type disorders, so we will review the interpre-tation of the functional tests that determine motility, which is esophageal manometry, and those that determine reflux gastroesophageal, acid and non-acid, which is the pH measure-ment with or without 24-h impedanciometry.
摘要：
超重和肥胖是一个公共卫生问题，世界卫生组织（WHO）在1997年将肥胖视为全球流行病。根据世界卫生组织的最新报告，超重和肥胖影响了欧洲近60％的成年人和三分之一的儿童。客观上,胃食管反流病(GERD)定义为通过内窥镜检查评估的特征性食管粘膜损伤和/或通过反流监测研究证明的病理性酸暴露.肥胖患者GERD的患病率在超重和肥胖患者中增加，GERD的临床症状尤其存在于仰卧位，这与24小时pH监测中夜间反流的更频繁发作有关，随着酸含量的增加，回流的数量也增加。在有症状的人群中，消化内镜检查检测到50%患者的糜烂性食管炎数据，24小时pH值测量诊断92％的非糜烂性反流病（NERD）患者。粘膜中持续性GERD的存在会影响食管运动，患者可能会发展为无效的食管运动型疾病，所以我们将回顾确定运动性的功能测试的干预，这是食道测压，和那些确定反流胃食管的，酸和非酸，这是有或没有24小时阻抗测量法的pH测量。
