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Abstract：
OBJECTIVE: Larger-than-planned capsulotomies can occur, yet their association with age and eye parameters remains poorly understood. This study aimed to assess capsulotomy enlargement after femtosecond laser treatment in cataract surgery and to explore a possible correlation of capsulotomy enlargement with age and eye parameters.
METHODS: This retrospective case series included consecutive patients diagnosed with cataracts between 05/2018 and 11/2019. Among them, patients within the age ranges of <18, 18-49, and ≥50 years were assigned to the childhood cataract (CC), young adult cataract (YAC), and age-related cataract (ARC) groups, respectively. The capsulotomy enlargement ratio (CER), age, degree of cataract, lens thickness (LT), axial length, and anterior chamber depth were recorded and analyzed.
RESULTS: A total of 155 participants (179 eyes) were enrolled. The CER was significantly different among the three groups (CC: 1.245 vs. YAC: 1.060 vs. ARC: 1.029, P<0.001). The CER was found to be independently associated with both age (β=-0.011 (0.001), P<0.001) and LT (β=-0.049 (0.017), P=0.006) in the CC group, but it was only independently correlated with age (β=-0.004 (0.001), P=0.002) in the YAC group and LT (β=-0.014 (0.007), P=0.048) in the ARC group.
CONCLUSIONS: Capsulotomy enlargement can occur after femtosecond laser treatment in cataract surgery, especially in the non-adult group. Age was a determinant of the CER in CC and YAC groups, while LT was an independent determinant of the CER in CC and ARC groups. These two factors should be taken into consideration for more precise sized capsulotomy.
METHODS: This retrospective case series included consecutive patients diagnosed with cataracts between 05/2018 and 11/2019. Among them, patients within the age ranges of <18, 18-49, and ≥50 years were assigned to the childhood cataract (CC), young adult cataract (YAC), and age-related cataract (ARC) groups, respectively. The capsulotomy enlargement ratio (CER), age, degree of cataract, lens thickness (LT), axial length, and anterior chamber depth were recorded and analyzed.
RESULTS: A total of 155 participants (179 eyes) were enrolled. The CER was significantly different among the three groups (CC: 1.245 vs. YAC: 1.060 vs. ARC: 1.029, P<0.001). The CER was found to be independently associated with both age (β=-0.011 (0.001), P<0.001) and LT (β=-0.049 (0.017), P=0.006) in the CC group, but it was only independently correlated with age (β=-0.004 (0.001), P=0.002) in the YAC group and LT (β=-0.014 (0.007), P=0.048) in the ARC group.
CONCLUSIONS: Capsulotomy enlargement can occur after femtosecond laser treatment in cataract surgery, especially in the non-adult group. Age was a determinant of the CER in CC and YAC groups, while LT was an independent determinant of the CER in CC and ARC groups. These two factors should be taken into consideration for more precise sized capsulotomy.
摘要：
目的：可以发生比计划更大的囊切开术，然而，他们与年龄和眼睛参数的关系仍然知之甚少。这项研究旨在评估白内障手术中飞秒激光治疗后的囊切开术扩大，并探讨囊切开术扩大与年龄和眼睛参数的可能相关性。
方法：本回顾性病例系列包括2018年5月至2019年11月被诊断为白内障的连续患者。其中,年龄在<18、18-49和≥50岁的患者被分配到儿童白内障（CC），青年白内障（YAC），和年龄相关性白内障（ARC）组，分别。囊切开术扩大率（CER），年龄,白内障的程度，透镜厚度(LT),轴向长度,记录和分析前房深度。
结果：共纳入155名参与者（179只眼）。三组的CER差异显著(CC：1.245vs.YAC：1.060vs.ARC:1.029,P<0.001)。发现CER与两个年龄都独立相关(β=-0.011(0.001)，P<0.001)和LT(β=-0.049(0.017)，CC组P=0.006），但它仅与年龄独立相关(β=-0.004(0.001)，YAC组和LT组的P=0.002）（β=-0.014（0.007），ARC组P=0.048)。
结论：在白内障手术中，飞秒激光治疗后可发生囊切开术扩大，尤其是在非成人群体中。年龄是CC和YAC组CER的决定因素，而LT是CC和ARC组CER的独立决定因素。对于更精确大小的囊切开术，应考虑这两个因素。
方法：本回顾性病例系列包括2018年5月至2019年11月被诊断为白内障的连续患者。其中,年龄在<18、18-49和≥50岁的患者被分配到儿童白内障（CC），青年白内障（YAC），和年龄相关性白内障（ARC）组，分别。囊切开术扩大率（CER），年龄,白内障的程度，透镜厚度(LT),轴向长度,记录和分析前房深度。
结果：共纳入155名参与者（179只眼）。三组的CER差异显著(CC：1.245vs.YAC：1.060vs.ARC:1.029,P<0.001)。发现CER与两个年龄都独立相关(β=-0.011(0.001)，P<0.001)和LT(β=-0.049(0.017)，CC组P=0.006），但它仅与年龄独立相关(β=-0.004(0.001)，YAC组和LT组的P=0.002）（β=-0.014（0.007），ARC组P=0.048)。
结论：在白内障手术中，飞秒激光治疗后可发生囊切开术扩大，尤其是在非成人群体中。年龄是CC和YAC组CER的决定因素，而LT是CC和ARC组CER的独立决定因素。对于更精确大小的囊切开术，应考虑这两个因素。
