Abstract:
Tuberculosis continues to be a major public health concern worldwide with almost 20-40% of the world\'s population being affected yearly. Cutaneous Tuberculosis (TB) is a rare and underdiagnosed entity that manifests in about 1-1.5% of extrapulmonary tuberculosis cases worldwide. Dermoscopy is a non-invasive tool which will be a useful aid to histopathology in the confirmation of the diagnosis alongside culture, and molecular techniques. This is a cross-sectional descriptive study that was conducted at a tertiary care center in Mumbai, India. A total of 31 patients were enrolled in this study; 14 males and 17 females. The mean duration of disease was 4.3 months and the average age was 31 years. There were 10 cases of lupus vulgaris, 7 scrofuloderma, 5 papulonecrotic tuberculid (PNT), 3 tuberculosis verrucosa cutis (TBVC), and 2 cases each of erythema induratum of Bazin, lichen scrofulosorum and resolved lupus vulgaris. All the lesions demonstrated orange yellow background suggestive of dermal granuloma. Other key dermoscopic features noted include yellowish-white scales, patulous follicles, white structureless areas, milia-like cysts, white streaks, pigment globules, hairpin and linear vessels. Newer findings such as the crown of vessels and perifollicular pallor in lichen scrofulosorum, and radiating white streaks in PNT were also noted. Dermoscopy of infective granulomas such as cutaneous tuberculosis is a less explored field of dermatology. Newer dermoscopic features of each clinical variant of cutaneous TB have been described.
摘要:
结核病仍然是世界范围内的主要公共卫生问题,每年几乎有20-40%的世界人口受到影响。皮肤结核病(TB)是一种罕见且未被诊断的实体,在全世界约1-1.5%的肺外结核病病例中表现出来。皮肤镜检查是一种非侵入性的工具,这将是一个有用的帮助,在确认诊断与培养,和分子技术。这是一项横断面描述性研究,在孟买的三级护理中心进行,印度。这项研究共招募了31名患者;14名男性和17名女性。平均病程4.3个月,平均年龄31岁。有10例寻常型狼疮,7个镰刀菌,5丘疹性结节(PNT),3疣状皮肤结核(TBVC),Bazin硬红斑各2例,苔藓和寻常性狼疮。所有病变均显示橙黄色背景,提示皮肤肉芽肿。注意到的其他关键皮肤镜特征包括黄白色鳞片,扁平毛囊,白色无结构区域,米利亚样囊肿,白色条纹,色素球,发夹和线性血管。较新的发现,如在苔藓中的血管冠和毛囊周围苍白,在PNT中也注意到辐射白色条纹。感染性肉芽肿如皮肤结核的皮肤镜检查是皮肤科研究较少的领域。已经描述了皮肤TB的每种临床变体的较新的皮肤镜特征。