Abstract：
Solitary fibrous tumour (SFT) is a mesenchymal neoplasm with variable behaviour, very rarely involving the genitourinary (GU) tract. Most reported cases correspond to isolated case reports. STAT6 immunohistochemistry is a more recent and reliable diagnostic marker. The pathology database of two tertiary institutes was searched for SFTs involving the GU tract. STAT6 strong diffuse nuclear staining confirmed the diagnosis in all four cases, and the NAB2::STAT6 fusion was demonstrated by NGS in one case. Two cases were diagnosed in needle biopsy, one involving the prostate and the other involving the seminal vesicle. One case corresponded to a pelvic mass inseparable from and infiltrating the prostate and bladder. The remainder represented an exceedingly rare involvement of the spermatic cord. Involvement by a SFT should be considered in the differential diagnosis of spindle cell lesions involving GU organs. STAT6 strong diffuse nuclear staining is an important ancillary tool, particularly in a biopsy.
摘要：
孤立性纤维性肿瘤（SFT）是一种具有可变行为的间充质肿瘤，很少涉及泌尿生殖道（GU）。大多数报告的病例对应于孤立的病例报告。STAT6免疫组织化学是较新和可靠的诊断标记。在两个大专院校的病理学数据库中搜索了涉及GU道的SFT。STAT6强弥漫性核染色证实了所有四例病例的诊断，NGS证实NAB2::STAT6融合1例。2例经穿刺活检确诊,一个涉及前列腺，另一个涉及精囊。一例对应于与前列腺和膀胱密不可分并浸润的盆腔肿块。其余代表精索极为罕见。在涉及GU器官的梭形细胞病变的鉴别诊断中，应考虑SFT的参与。STAT6强弥漫性核染色是重要的辅助工具,特别是在活检中。
