关键词: diffuse b-cell non-hodgkin lymphoma histopathology invasive lobular breast carcinoma multi-disciplinary approach multiple primary malignancies

来  源:   DOI:10.7759/cureus.46903   PDF(Pubmed)

Abstract:
Multiple primary malignancies (MPMs) are defined as two or more histopathologically distinct malignancies in the same individual. MPMs are classified as synchronous when tumors are diagnosed within six months of each other. The most common malignancies in MPMs are melanoma, breast, lung, and prostate cancer. Synchronous lymphoma and solid tumors are relatively rare. In these cases, a multi-disciplinary approach to treatment is essential. The early detection of additional primary malignancies such as myeloid and lymphatic tumors will enable prompt management with curative intent. The authors present a case of diffuse B-cell non-Hodgkin lymphoma and invasive lobular breast carcinoma presented as a chylous pleural effusion.
摘要:
多发性原发性恶性肿瘤(MPM)被定义为同一个体中的两种或更多种组织病理学上不同的恶性肿瘤。当肿瘤在彼此的六个月内被诊断出时,MPM被分类为同步的。MPM中最常见的恶性肿瘤是黑色素瘤,乳房,肺,和前列腺癌。同步淋巴瘤和实体瘤相对罕见。在这些情况下,多学科的治疗方法至关重要。早期发现其他原发性恶性肿瘤,例如骨髓和淋巴肿瘤,将能够迅速进行治疗。作者介绍了一例弥漫性B细胞非霍奇金淋巴瘤和浸润性小叶乳腺癌,表现为乳糜性胸腔积液。
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