Abstract：
OBJECTIVE: Topic treatment can be useful to improve short and long-term nasal outcomes after nasal surgery, reducing discomfort and risk of synechia. This study aimed at evaluating the effect on clinical outcomes of nasal packaging using Fitostimoline® gauze in FESS and septoplasty.
METHODS: A case-control study on hospitalized patients was performed in a tertiary referral center. The control group included 20 patients treated with the standard surgical protocol for septoplasty and standard nasal packaging; treatment group included 21 patients underwent same surgical procedure but in whom the nasal tampon was wrapped with a gauze containing Fitostimoline® before being placed into the nose.
RESULTS: Patients in treatment group had better outcomes than control; nasal mucosa showed better healing - recovery of normal color- in those patients in whom we applied the Fitostimoline® gauze around tampons. Moreover, 100 % patients in the treatment group did not refer discomfort during at tampon removal versus 60 % subjects in the control group who referred pain, tension or tearing during the same action.
CONCLUSIONS: Our results, although preliminary because of the small cohort of subjects included, suggest that the apposition of a gauze with Fitostimoline® after nasal surgery might improve the mucosal healing with consequent reduction of patients discomfort during the post-surgical period.
METHODS: A case-control study on hospitalized patients was performed in a tertiary referral center. The control group included 20 patients treated with the standard surgical protocol for septoplasty and standard nasal packaging; treatment group included 21 patients underwent same surgical procedure but in whom the nasal tampon was wrapped with a gauze containing Fitostimoline® before being placed into the nose.
RESULTS: Patients in treatment group had better outcomes than control; nasal mucosa showed better healing - recovery of normal color- in those patients in whom we applied the Fitostimoline® gauze around tampons. Moreover, 100 % patients in the treatment group did not refer discomfort during at tampon removal versus 60 % subjects in the control group who referred pain, tension or tearing during the same action.
CONCLUSIONS: Our results, although preliminary because of the small cohort of subjects included, suggest that the apposition of a gauze with Fitostimoline® after nasal surgery might improve the mucosal healing with consequent reduction of patients discomfort during the post-surgical period.
摘要：
目的：主题治疗可用于改善鼻部手术后的短期和长期鼻部预后，减少不适和粘连的风险。这项研究旨在评估在FESS和鼻中隔成形术中使用Fitostimoline®纱布进行鼻部包装对临床结果的影响。
方法：在三级转诊中心对住院患者进行了病例对照研究。对照组包括20例接受标准的鼻中隔成形术和标准鼻部包装手术方案治疗的患者；治疗组包括21例接受相同手术程序的患者，但其中鼻塞在放入鼻子之前用含有Fitostimoline®的纱布包裹。
结果：治疗组患者的治疗效果优于对照组；我们在卫生棉条周围使用Fitostimoline®纱布的患者鼻粘膜显示更好的愈合-恢复正常颜色。此外，治疗组中100％的患者在取出卫生棉条时没有提到不适，而对照组中有60％的受试者提到疼痛，在同一动作中紧张或撕裂。
结论：我们的结果，尽管是初步的，因为包括了一小部分受试者，建议鼻部手术后纱布与Fitostimoline®并置可能会改善粘膜愈合，从而减少术后患者的不适。
方法：在三级转诊中心对住院患者进行了病例对照研究。对照组包括20例接受标准的鼻中隔成形术和标准鼻部包装手术方案治疗的患者；治疗组包括21例接受相同手术程序的患者，但其中鼻塞在放入鼻子之前用含有Fitostimoline®的纱布包裹。
结果：治疗组患者的治疗效果优于对照组；我们在卫生棉条周围使用Fitostimoline®纱布的患者鼻粘膜显示更好的愈合-恢复正常颜色。此外，治疗组中100％的患者在取出卫生棉条时没有提到不适，而对照组中有60％的受试者提到疼痛，在同一动作中紧张或撕裂。
结论：我们的结果，尽管是初步的，因为包括了一小部分受试者，建议鼻部手术后纱布与Fitostimoline®并置可能会改善粘膜愈合，从而减少术后患者的不适。
