关键词: Esophageal stricture Esophagectomy Gastroesophageal reflux disease Systemic sclerosis

来  源:   DOI:10.1186/s40792-023-01727-3   PDF(Pubmed)

Abstract:
BACKGROUND: Systemic sclerosis (SSc) is an autoimmune disease characterized by frequent esophageal involvement. However, there are few reports on esophagectomy for esophageal strictures associated with SSc. Herein, we present a case of successful treatment of an esophageal stricture associated with SSc through subtotal esophagectomy.
METHODS: A 53-year-old female patient was diagnosed with SSc, interstitial pneumonia, and gastroesophageal reflux disease (GERD). The patient developed an esophageal ulcer and benign stricture that required a subtotal esophagectomy 10 years after the diagnosis. Histopathological findings revealed thinning of the muscle layer, a characteristic feature of SSc. The patient was free of dysphagia or regurgitation.
CONCLUSIONS: An esophagectomy is a valuable option for treating esophageal strictures in SSc. Therefore, surgical approaches should be established for patients with SSc.
摘要:
背景:系统性硬化症(SSc)是一种自身免疫性疾病,其特征是频繁的食管受累。然而,关于食管狭窄与SSc相关的食管切除术的报道很少。在这里,我们介绍了一例通过食管次全切除术成功治疗与SSc相关的食管狭窄的病例。
方法:一名53岁女性患者被诊断为SSc,间质性肺炎,胃食管反流病(GERD)。患者出现食管溃疡和良性狭窄,需要在诊断后10年进行食管次全切除术。组织病理学发现肌肉层变薄,SSc的一个特征。患者没有吞咽困难或反流。
结论:食管切除术是治疗SSc食管狭窄的一种有价值的选择。因此,SSc患者应建立手术方法。
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