Abstract：
OBJECTIVE: Meniere\'s disease (MD) is a disabling condition with symptoms, such as hearing loss, dizziness, and tinnitus. Surgery is the last resort option for managing MD when other treatments are not effective. Surgical labyrinthectomy (SL) is less commonly performed than vestibular neurectomy or chemical labyrinthectomy. We sought to assess the efficacy and safety of the SL procedure.
METHODS: A retrospective study was carried out involving a cohort of 25 patients with disabling and drug-resistant MD, who underwent SL performed by the same surgeon at University Hospital UCL Namur between 2009 and 2019. All patients considered their hearing non-functional and requested a radical therapeutic option. We compared subjective and objective measures before and after surgery, retrieved from patient medical records.
RESULTS: The difference between the Dizziness Handicap Inventory scores before and after surgery was statistically significant (p < 0.01). 81% of patients being satisfied with surgery. No post-operative complications occurred. Following SL, 14 patients evolved well, both subjectively and clinically, without any further vestibular workup required, which was offered to the other patients. All had a total deafness on the operated side, as expected, while four benefited from multidisciplinary rehabilitation because of persistent tinnitus. The scientific literature on this topic was reviewed, compared, and discussed.
CONCLUSIONS: Based on our results, SL represents an efficient and safe approach to achieve vestibular deafferentation in patients with unilateral, disabling, and treatment-resistant MD, with non-functional hearing.
METHODS: A retrospective study was carried out involving a cohort of 25 patients with disabling and drug-resistant MD, who underwent SL performed by the same surgeon at University Hospital UCL Namur between 2009 and 2019. All patients considered their hearing non-functional and requested a radical therapeutic option. We compared subjective and objective measures before and after surgery, retrieved from patient medical records.
RESULTS: The difference between the Dizziness Handicap Inventory scores before and after surgery was statistically significant (p < 0.01). 81% of patients being satisfied with surgery. No post-operative complications occurred. Following SL, 14 patients evolved well, both subjectively and clinically, without any further vestibular workup required, which was offered to the other patients. All had a total deafness on the operated side, as expected, while four benefited from multidisciplinary rehabilitation because of persistent tinnitus. The scientific literature on this topic was reviewed, compared, and discussed.
CONCLUSIONS: Based on our results, SL represents an efficient and safe approach to achieve vestibular deafferentation in patients with unilateral, disabling, and treatment-resistant MD, with non-functional hearing.
摘要：
目的：梅尼埃病（MD）是一种有症状的致残疾病，比如听力损失,头晕,还有耳鸣.当其他治疗无效时，手术是治疗MD的最后选择。手术迷路切除术（SL）不如前庭神经切除术或化学迷路切除术。我们试图评估SL手术的有效性和安全性。
方法：进行了一项回顾性研究，涉及25名致残和耐药MD患者，在2009年至2019年期间，他在UCLNamur大学医院接受了同一位外科医生进行的SL。所有患者都认为他们的听力无功能，并要求进行彻底的治疗选择。我们比较了手术前后的主观和客观指标，从病人的医疗记录中检索。
结果：手术前后头晕障碍量表评分差异有统计学意义（p<0.01）。81%的患者对手术满意。术后无并发症发生。在SL之后，14名患者进化良好，主观上和临床上，无需任何进一步的前庭检查，提供给其他患者。手术侧都有完全耳聋，正如预期的那样，虽然四个受益于多学科康复，因为持续的耳鸣。回顾了有关该主题的科学文献，比较,并讨论。
结论：根据我们的结果，SL代表了一种有效和安全的方法来实现单侧患者的前庭去传入，禁用,和治疗抗性MD，听力不正常。
方法：进行了一项回顾性研究，涉及25名致残和耐药MD患者，在2009年至2019年期间，他在UCLNamur大学医院接受了同一位外科医生进行的SL。所有患者都认为他们的听力无功能，并要求进行彻底的治疗选择。我们比较了手术前后的主观和客观指标，从病人的医疗记录中检索。
结果：手术前后头晕障碍量表评分差异有统计学意义（p<0.01）。81%的患者对手术满意。术后无并发症发生。在SL之后，14名患者进化良好，主观上和临床上，无需任何进一步的前庭检查，提供给其他患者。手术侧都有完全耳聋，正如预期的那样，虽然四个受益于多学科康复，因为持续的耳鸣。回顾了有关该主题的科学文献，比较,并讨论。
结论：根据我们的结果，SL代表了一种有效和安全的方法来实现单侧患者的前庭去传入，禁用,和治疗抗性MD，听力不正常。
