PDF(Pubmed)
Abstract：
Waist circumference can be used as an anthropometric measure to assess central obesity and is easier and more convenient than the waist-to-hip ratio in identifying the risk of obesity and medical problems. Most studies showing an association between obesity and infertility in women have used BMI to measure obesity. Our goal was to examine any potential association between waist circumference and infertility.
This cross-sectional study, which formed part of the National Health and Nutrition Examination Survey (NHANES), comprised women ages 18 to 45 between 2017 and 2020. Participants without waist circumference data or information on infertility were removed from the study. The independent relationship between waist circumference and infertility was investigated using weighted binary logistic regression and subgroup analysis.
We investigated 1509 participants and discovered that the prevalence of infertility rose as the WC trisection rose. (tertile 1, 7.55%; tertile 2, 10.56%; tertile 3, 15.28%; trend < 0.001). Multivariate logistic regression showed that after total adjustment, higher WC levels were associated with an increased likelihood of infertility in women (OR1.02; 95% CI 1.01-1.03), and There was a 2% rise in the incidence of infertility for every unit (cm) increased WC. Subgroup analysis and interaction tests showed no significant dependence of the effects of marital status, diabetes, hypertension, and high cholesterol on the association between WC and infertility (p for all interaction tests > 0.05). The inflection point of the positive non-linear relationship between WC and infertility was 116.6 cm.
Excessive waist circumference assessment may increase the probability of infertility, and more attention should be paid to the management of waist circumference should be given more attention.
This cross-sectional study, which formed part of the National Health and Nutrition Examination Survey (NHANES), comprised women ages 18 to 45 between 2017 and 2020. Participants without waist circumference data or information on infertility were removed from the study. The independent relationship between waist circumference and infertility was investigated using weighted binary logistic regression and subgroup analysis.
We investigated 1509 participants and discovered that the prevalence of infertility rose as the WC trisection rose. (tertile 1, 7.55%; tertile 2, 10.56%; tertile 3, 15.28%; trend < 0.001). Multivariate logistic regression showed that after total adjustment, higher WC levels were associated with an increased likelihood of infertility in women (OR1.02; 95% CI 1.01-1.03), and There was a 2% rise in the incidence of infertility for every unit (cm) increased WC. Subgroup analysis and interaction tests showed no significant dependence of the effects of marital status, diabetes, hypertension, and high cholesterol on the association between WC and infertility (p for all interaction tests > 0.05). The inflection point of the positive non-linear relationship between WC and infertility was 116.6 cm.
Excessive waist circumference assessment may increase the probability of infertility, and more attention should be paid to the management of waist circumference should be given more attention.
摘要：
■腰围可用作人体测量指标来评估中心性肥胖，并且在识别肥胖和医疗问题的风险方面比腰臀比更容易，更方便。大多数研究表明女性肥胖与不孕症之间存在关联，已经使用BMI来衡量肥胖。我们的目标是检查腰围和不孕症之间的任何潜在关联。
■这项横断面研究，这是国家健康和营养检查调查(NHANES)的一部分，包括2017年至2020年18至45岁的女性。没有腰围数据或不孕症信息的参与者从研究中删除。采用加权二元logistic回归和亚组分析探讨腰围与不孕症的独立关系。
■我们调查了1509名参与者，发现不孕症的患病率随着WC三分法的上升而上升。（三元组1，7.55%；三元组2，10.56%；三元组3，15.28%；趋势<0.001）。多因素logistic回归显示，经过总调整后，较高的WC水平与女性不孕的可能性增加相关(OR1.02;95%CI1.01-1.03)，WC每增加一个单位（cm），不孕的发病率就会增加2％。亚组分析和交互检验显示婚姻状况的影响没有显著的依赖性，糖尿病,高血压,和高胆固醇对WC和不孕症之间的关联（所有交互测试的p>0.05）。WC与不孕症呈正非线性关系的拐点为116.6cm。
■过度的腰围评估可能会增加不孕的概率，应更加重视腰围的管理。
■这项横断面研究，这是国家健康和营养检查调查(NHANES)的一部分，包括2017年至2020年18至45岁的女性。没有腰围数据或不孕症信息的参与者从研究中删除。采用加权二元logistic回归和亚组分析探讨腰围与不孕症的独立关系。
■我们调查了1509名参与者，发现不孕症的患病率随着WC三分法的上升而上升。（三元组1，7.55%；三元组2，10.56%；三元组3，15.28%；趋势<0.001）。多因素logistic回归显示，经过总调整后，较高的WC水平与女性不孕的可能性增加相关(OR1.02;95%CI1.01-1.03)，WC每增加一个单位（cm），不孕的发病率就会增加2％。亚组分析和交互检验显示婚姻状况的影响没有显著的依赖性，糖尿病,高血压,和高胆固醇对WC和不孕症之间的关联（所有交互测试的p>0.05）。WC与不孕症呈正非线性关系的拐点为116.6cm。
■过度的腰围评估可能会增加不孕的概率，应更加重视腰围的管理。
